H
Hiroyuki Yokoyama
Researcher at Tohoku University
Publications - 140
Citations - 3354
Hiroyuki Yokoyama is an academic researcher from Tohoku University. The author has contributed to research in topics: Semiconductor laser theory & Laser. The author has an hindex of 34, co-authored 132 publications receiving 3112 citations. Previous affiliations of Hiroyuki Yokoyama include Yamagata University.
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Journal ArticleDOI
Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics
Masatoshi Inoue,Masatoshi Inoue,Atsuya Takeuchi,Satoshi Manita,Shin-ichiro Horigane,Shin-ichiro Horigane,Masayuki Sakamoto,Ryosuke Kawakami,Ryosuke Kawakami,Kazushi Yamaguchi,Kouhei Otomo,Hiroyuki Yokoyama,Ryang Kim,Tatsushi Yokoyama,Sayaka Takemoto-Kimura,Manabu Abe,Michiko Okamura,Yayoi Kondo,Sean Quirin,Charu Ramakrishnan,Takeshi Imamura,Kenji Sakimura,Tomomi Nemoto,Tomomi Nemoto,Masanobu Kano,Hajime Fujii,Karl Deisseroth,Kazuo Kitamura,Kazuo Kitamura,Haruhiko Bito +29 more
TL;DR: The next-generation quadricolor GECI suite, XCaMPs, offer a critical enhancement of solution space in studies of complex neuronal circuit dynamics, and reveal spatiotemporal constraints of dendritic inhibition in layer 1 in vivo.
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Effect of thioperamide, a histamine H3 receptor antagonist, on electrically induced convulsions in mice
TL;DR: The blockade by mepyramine of the thioperamide-induced decrease in seizure susceptibility indicates that histamine released by thiOPERamide from the histaminergic nerve terminals interacts with the histamine H1 receptors of postsynaptic neurons, supporting the hypothesis that the central Histaminergic system is involved in the inhibition of seizures.
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Visualizing hippocampal neurons with in vivo two-photon microscopy using a 1030 nm picosecond pulse laser
Ryosuke Kawakami,Kazuaki Sawada,Aya Sato,Terumasa Hibi,Yuichi Kozawa,Shunichi Sato,Hiroyuki Yokoyama,Tomomi Nemoto +7 more
TL;DR: A novel semiconductor-laser-based light source with a wavelength of 1030 nm that can generate pulses of 5-picosecond duration with 2-W output power, and a 20-MHz repetition rate and a system to secure the head of the mouse under an upright microscope stage that has a horizontal adjustment mechanism are developed.
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Lateral resolution enhancement of laser scanning microscopy by a higher-order radially polarized mode beam
Yuichi Kozawa,Terumasa Hibi,Aya Sato,Hibiki Horanai,Makoto Kurihara,Nobuyuki Hashimoto,Hiroyuki Yokoyama,Tomomi Nemoto,Shunichi Sato +8 more
TL;DR: It is demonstrated that the lateral resolution of confocal laser scanning microscopy is dramatically improved by a higher-order radially polarized (HRP) beam with six concentric rings generated simply by inserting liquid crystal devices in front of an objective lens.