H
Hisamichi Aizawa
Researcher at Kurume University
Publications - 120
Citations - 3816
Hisamichi Aizawa is an academic researcher from Kurume University. The author has contributed to research in topics: COPD & Asthma. The author has an hindex of 29, co-authored 120 publications receiving 3597 citations.
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Journal ArticleDOI
COPD in Japan : the Nippon COPD Epidemiology study
Yoshinosuke Fukuchi,Masaharu Nishimura,Masakazu Ichinose,Mitsuru Adachi,Atsushi Nagai,Takayuki Kuriyama,Keiji Takahashi,Koichi Nishimura,Shinichi Ishioka,Hisamichi Aizawa,Carol A. Zaher +10 more
TL;DR: The Nippon COPD Epidemiology (NICE) Study used spirometry to measure prevalence of airflow limitation in Japanese adults and found that smoking rates in Japan are high and prevalence of COPD is high.
Journal ArticleDOI
Interleukin-18 production and pulmonary function in COPD
Haruki Imaoka,Tomoaki Hoshino,Satoko Takei,Takashi Kinoshita,Masaki Okamoto,Tomotaka Kawayama,Seiya Kato,Hiroshi Iwasaki,Kentarou Watanabe,Hisamichi Aizawa +9 more
TL;DR: Overproduction of interleukin-18 in the lungs may be involved in the pathogenesis of chronic obstructive pulmonary disease.
Journal ArticleDOI
Periostin, a Matricellular Protein, Plays a Role in the Induction of Chemokines in Pulmonary Fibrosis
Masaru Uchida,Hiroshi Shiraishi,Shoichiro Ohta,Kazuhiko Arima,Kazuto Taniguchi,Shoichi Suzuki,Masaki Okamoto,Shawn K. Ahlfeld,Koichi Ohshima,Seiya Kato,Shuji Toda,Hironori Sagara,Hisamichi Aizawa,Tomoaki Hoshino,Simon J. Conway,Shinichiro Hayashi,Kenji Izuhara +16 more
TL;DR: It is concluded that periostin plays a unique role as an inducer of chemokines to recruit neutrophils and macrophages important in the process of pulmonary fibrosis in BLM-administered model mice, suggesting a therapeutic potential for periastin in IPF and drug-induced ILD.
Journal ArticleDOI
B7-DC Regulates Asthmatic Response by an IFN-γ-Dependent Mechanism
Koichiro Matsumoto,Hiromasa Inoue,Takako Nakano,Miyuki Tsuda,Yuki Yoshiura,Satoru Fukuyama,Fumihiko Tsushima,Tomoaki Hoshino,Hisamichi Aizawa,Hisaya Akiba,Drew M. Pardoll,Nobuyuki Hara,Hideo Yagita,Miyuki Azuma,Yoichi Nakanishi +14 more
TL;DR: A unique role for B7-DC in the regulation of asthmatic response through an IFN-γ-dependent, but PD-1-independent, mechanism is suggested.
Periostin, a matricellular protein, plays a role in the induction of chemokines in pulmonary fibrosis
Masaru Uchida,Hiroshi Shiraishi,Shoichiro Ohta,Kazuhiko Arima,Kazuto Taniguchi,Shoichi Suzuki,Masaki Okamoto,Shawn K. Ahlfeld,Koichi Ohshima,Seiya Kato,Shuji Toda,Hironori Sagara,Hisamichi Aizawa,Tomoaki Hoshino,Simon J. Conway,Shinichiro Hayashi,Kenji Izuhara +16 more
TL;DR: In this article, a decrease in the preceding recruitment of neutrophils and macrophages in the lungs because of a lower production of chemokines and proinflammatory cytokines was found.