H
Hiromasa Inoue
Researcher at Kagoshima University
Publications - 235
Citations - 7845
Hiromasa Inoue is an academic researcher from Kagoshima University. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 42, co-authored 219 publications receiving 6799 citations. Previous affiliations of Hiromasa Inoue include Kurume University & Kyushu University.
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Journal ArticleDOI
A summary of the new GINA strategy: a roadmap to asthma control.
Helen K. Reddel,Eric D. Bateman,Allan B. Becker,Louis-Philippe Boulet,Alvaro A. Cruz,Jeffrey M. Drazen,Tari Haahtela,Suzanne S. Hurd,Hiromasa Inoue,Johan C. de Jongste,Robert F. Lemanske,Mark L Levy,Paul M. O'Byrne,Pierluigi Paggiaro,Søren Pedersen,Emilio Pizzichini,Manuel Soto-Quiroz,Stanley J. Szefler,Gary W.K. Wong,J. Mark FitzGerald +19 more
TL;DR: The changes include a revised asthma definition, tools for assessing symptom control and risk factors for adverse outcomes, and updated strategies for adaptation and implementation of GINA recommendations.
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SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses
Yoh Ichi Seki,Hiromasa Inoue,Naoko Nagata,Katsuhiko Hayashi,Satoru Fukuyama,Koichiro Matsumoto,Okiru Komine,Shinjiro Hamano,Kunisuke Himeno,Kyoko Inagaki-Ohara,Nicholas A. Cacalano,Anne O'Garra,Tadahilo Oshida,Hirohisa Saito,James A. Johnston,Akihiko Yoshimura,Masato Kubo +16 more
TL;DR: It is suggested that SOCS-3 has an important role in regulating the onset and maintenance of TH2-mediated allergic immune disease, and may be a new therapeutic target for the development of antiallergic drugs.
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Regulation of αβ/γδ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
Kenji Tanigaki,Masayuki Tsuji,Norio Yamamoto,Hua Han,Jun Tsukada,Hiromasa Inoue,Masato Kubo,Tasuku Honjo +7 more
TL;DR: It is demonstrated that Notch/RBP-J signaling regulates γδ T cell generation and migration, αβ T cell maturation, terminal differentiation of CD4 + T cells into Th1/Th2 cells, and activation of T cells.
Journal ArticleDOI
Revisiting Type 2‐high and Type 2‐low airway inflammation in asthma: current knowledge and therapeutic implications
Douglas S. Robinson,Marc Humbert,Roland Buhl,Alvaro A. Cruz,Hiromasa Inoue,Stephan Korom,Nicola A. Hanania,Parameswaran Nair +7 more
TL;DR: Anticipating and understanding the heterogeneity of asthma and subsequent improved characterization of different phenotypes and endotypes must guide the selection of treatment to meet individual patients’ needs.
Journal ArticleDOI
GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents
Helen K. Reddel,J. Mark FitzGerald,Eric D. Bateman,Leonard B. Bacharier,Allan B. Becker,Guy Brusselle,Roland Buhl,Alvaro A. Cruz,Louise Fleming,Hiromasa Inoue,Fanny W.S. Ko,Jerry A. Krishnan,Mark L Levy,Jiangtao Lin,Søren Pedersen,Aziz Sheikh,Arzu Yorgancioglu,Louis-Philippe Boulet +17 more
TL;DR: The Global Initiative for Asthma no longer recommends treating adults/adolescents with asthma with short-acting bronchodilators alone and they should receive symptom-driven or a daily corticosteroid-containing inhaler, to reduce risk of severe exacerbations.