H
Hisashi Uhara
Researcher at Sapporo Medical University
Publications - 178
Citations - 3068
Hisashi Uhara is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Melanoma & Medicine. The author has an hindex of 27, co-authored 152 publications receiving 2444 citations. Previous affiliations of Hisashi Uhara include Shinshu University.
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Journal ArticleDOI
Nivolumab-related myasthenia gravis with myositis and myocarditis in Japan.
Shigeaki Suzuki,Nobuhisa Ishikawa,Fumie Konoeda,Nobuhiko Seki,Satoshi Fukushima,Kikuko Takahashi,Hisashi Uhara,Yoshikazu Hasegawa,Shinichiro Inomata,Yasushi Otani,Kenji Yokota,T. Hirose,Ryo Tanaka,Norihiro Suzuki,Makoto Matsui +14 more
TL;DR: The prompt and correct recognition of MG following treatment with immune checkpoint inhibitors in patients with cancer is important and postintervention status showed that pharmacologic remission or minimal manifestations were obtained in 4 patients; however, 2 patients died.
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Acetylcholine receptor binding antibody-associated myasthenia gravis and rhabdomyolysis induced by nivolumab in a patient with melanoma
Takushi Shirai,Tasuku Sano,Fuminao Kamijo,Nana Saito,Tomomi Miyake,Minori Kodaira,Nagaaki Katoh,Kenichi Nishie,Ryuhei Okuyama,Hisashi Uhara +9 more
TL;DR: An 81-year-old woman with metastatic melanoma, in whom myasthenia gravis and rhabdomyolysis developed after nivolumab monotherapy, was reported, strongly suggesting that the myasta gravis was a nivolinumab-related immune adverse event.
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Key points in dermoscopic differentiation between early acral melanoma and acral nevus.
TL;DR: The three‐step algorithm for the management of acral melanocytic lesions, which surely aids us in effectively detecting early acrals melanoma and in reducing unnecessary resection of benign nevus is described.
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Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level.
Kaori Sakaizawa,Yasufumi Goto,Yukiko Kiniwa,Aya Uchiyama,Kazutoshi Harada,Shinji Shimada,Toshiaki Saida,Soldano Ferrone,Minoru Takata,Hisashi Uhara,Ryuhei Okuyama +10 more
TL;DR: Melanoma cells show clonal heterogeneity and CTC genotyping may be crucial for successful molecular-targeted therapy, and polyclonal BRAF mutations were identified in one patient and concomitant mutations in BRAF and KIT were identify in another patient.
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A proposal for a TNM staging system for extramammary Paget disease: Retrospective analysis of 301 patients with invasive primary tumors.
Kuniaki Ohara,Yasuhiro Fujisawa,Koji Yoshino,Yoshio Kiyohara,Takafumi Kadono,Yozo Murata,Hisashi Uhara,Naohito Hatta,Hiroshi Uchi,Shigeto Matsushita,Tatsuya Takenouchi,Toshihiko Hayashi,Kenichi Yoshimura,Manabu Fujimoto +13 more
TL;DR: A TNM staging system for EMPD is proposed using simple factors for classification that could provide important prognostic information in managing EMPD and accumulation of more patient data and further revision of the system are required.