H
Hogyoung Kim
Researcher at Tulane University
Publications - 61
Citations - 2473
Hogyoung Kim is an academic researcher from Tulane University. The author has contributed to research in topics: Microvesicles & Cancer. The author has an hindex of 26, co-authored 54 publications receiving 2026 citations. Previous affiliations of Hogyoung Kim include Louisiana State University & LSU Health Sciences Center New Orleans.
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Journal ArticleDOI
Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-κB through Akt and p38 inhibition in RAW 264.7 macrophage cells
Hogyoung Kim,Bhushan Shrestha,Soyeon Lim,Deok Hyo Yoon,Woochul Chang,Dong Jik Shin,Sang Kuk Han,Sang Min Park,Jung Hee Park,Hae Il Park,Jae-Mo Sung,Yangsoo Jang,Namsik Chung,Ki-Chul Hwang,Tae Woong Kim +14 more
TL;DR: Results suggest that cordycepin inhibits the production of NO production by down-regulation of iNOS and COX-2 gene expression via the suppression of NF-kappaB activation, Akt and p38 phosphorylation, and may provide a potential therapeutic approach for inflammation-associated disorders.
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High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer
Amrita Datta,Hogyoung Kim,Lauren McGee,Adedoyin Johnson,Sudha Talwar,Juan J. Marugan,Noel Southall,Xin Hu,Madhu Lal,Debasis Mondal,Marc Ferrer,Asim B. Abdel-Mageed +11 more
TL;DR: The findings implicate the potential utility of drug-repurposing as novel adjunct therapeutic strategies in advanced cancer.
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Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
Amrita Datta,Hogyoung Kim,Madhu Lal,Lauren McGee,Adedoyin Johnson,Ahmed A Moustafa,Jennifer Jones,Debasis Mondal,Marc Ferrer,Asim B. Abdel-Mageed +9 more
TL;DR: Manumycin-A (MA), a natural microbial metabolite, was identified as an inhibitor of exosome biogenesis and secretion by castration-resistant prostate cancer (CRPC) C4-2B, but not the normal RWPE-1, cells.
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Poly(ADP-Ribose) Polymerase-1 Is a Determining Factor in Crm1-Mediated Nuclear Export and Retention of p65 NF-κB upon TLR4 Stimulation
Mourad Zerfaoui,Youssef Errami,Amarjit S. Naura,Yasuhiro Suzuki,Hogyoung Kim,Jihang Ju,Tao Liu,Chetan P. Hans,Jong G. Kim,Zakaria Y. Abd Elmageed,Shahriar Koochekpour,Andrew D. Catling,A. Hamid Boulares +12 more
TL;DR: It is shown that PARP-1 inhibition by gene knockout, knockdown, or pharmacologic blockade prevented p65 NF-κB nuclear translocation in smooth muscle cells upon TLR4 stimulation, NF-σκB DNA-binding activity, and subsequent inducible NO synthase and ICAM-1 expression.
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Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage
Hogyoung Kim,Deok Hyo Yoon,Won-Ho Lee,Sang Kuk Han,Bhushan Shrestha,Chun Hoi Kim,Mi Hee Lim,Woochul Chang,Soyeon Lim,Sunga Choi,Won O. Song,Jae-Mo Sung,Ki-Chul Hwang,Tae Woong Kim +13 more
TL;DR: It is suggested that PLBF inhibits the production of NO and PGE2 through the down-regulation of iNOS and COX-2 gene expression via ROS-based NF-kappaB and MAPKs activation, and may provide a potential therapeutic approach for inflammation-associated disorders.