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Jennifer Jones

Researcher at National Institutes of Health

Publications -  205
Citations -  12679

Jennifer Jones is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Medicine & Extracellular vesicle. The author has an hindex of 35, co-authored 158 publications receiving 8126 citations. Previous affiliations of Jennifer Jones include Montana State University & Brigham and Women's Hospital.

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Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, +417 more
TL;DR: The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities, and a checklist is provided with summaries of key points.
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Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper

TL;DR: This position paper was written by the participants of the workshop to give an overview of the current state of knowledge in the field and to clarify that incomplete knowledge – of the nature of EV(-RNA)s and of how to effectively and reliably study them – currently prohibits the implementation of gold standards in EV-RNA research.
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Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

TL;DR: It is demonstrated that decreased levels of Sox2 result in precocious hair cell differentiation and an over production of inner hair cells and that these effects are likely mediated through an antagonistic interaction between Sox2 and the bHLH molecule Atoh1.
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Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

TL;DR: N nanoFACS, a high-resolution flow cytometric method that utilizes light scattering and fluorescence parameters along with sample enumeration, is used to evaluate various labels and develops a robust EV staining strategy that robustly labels individual EVs.
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Efficient production and enhanced tumor delivery of engineered extracellular vesicles.

TL;DR: The Scavenger Receptor Class A family (SR-A) is identified as a novel monocyte/macrophage uptake receptor for EV and blockade of SR-A with dextran sulfate dramatically decreased EV liver clearance in mice, while enhancing tumor accumulation.