H
Hong Sheng Cheng
Researcher at Nanyang Technological University
Publications - 28
Citations - 461
Hong Sheng Cheng is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 18 publications receiving 223 citations. Previous affiliations of Hong Sheng Cheng include Monash University Malaysia Campus.
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Journal ArticleDOI
Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence.
Hong Sheng Cheng,Wei Ren Tan,Zun Siong Low,Charlie Marvalim,Justin Yin Hao Lee,Nguan Soon Tan +5 more
TL;DR: The future design of better PPAR modulators with minimal off-target effects, high selectivity, superior bioavailability, and pharmacokinetics are anticipated, which will open new possibilities for PPAR ligands in medicine.
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Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment.
TL;DR: The present review aims to summarize recent evidence about the roles of nuclear receptors in tumor-supporting cells and their implications for malignant processes such as tumor proliferation, evasion of immune surveillance, angiogenesis, chemotherapeutic resistance, and metastasis.
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Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects
TL;DR: It has been demonstrated that geraniin possesses antioxidant, antimicrobial, anticancer, cytoprotective, immune-modulatory, analgesic properties besides exerting promising therapeutic effects on hypertension, cardiovascular disease and metabolic dysregulation.
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Increased susceptibility of post-weaning rats on high-fat diet to metabolic syndrome.
TL;DR: The post-weaning rats on high-fat diet is a better and less time-consuming model for metabolic syndrome research.
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The Ameliorative Effects of a Tocotrienol-Rich Fraction on the AGE-RAGE Axis and Hypertension in High-Fat-Diet-Fed Rats with Metabolic Syndrome.
TL;DR: Treatment with a TRF exhibited protective effects on the cardiovascular and liver health in addition to the amelioration of plasma redox imbalance and AGE-RAGE activation in high-fat-diet-treated rats.