H
Hong Wang
Researcher at University of Colorado Denver
Publications - 18
Citations - 3017
Hong Wang is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Lipoprotein lipase & Insulin resistance. The author has an hindex of 10, co-authored 18 publications receiving 2632 citations.
Papers
More filters
Journal ArticleDOI
The Metabolic Syndrome
Marc-Andre Cornier,Dana Dabelea,Teri L. Hernandez,Rachel C. Lindstrom,Amy J. Steig,Nicole R. Stob,Rachael E. Van Pelt,Hong Wang,Robert H. Eckel +8 more
TL;DR: The "metabolic syndrome" is a clustering of components that reflect overnutrition, sedentary lifestyles, and resultant excess adiposity that is associated with an approximate doubling of cardiovascular disease risk and a 5-fold increased risk for incident type 2 diabetes mellitus.
Journal ArticleDOI
Lipoprotein lipase: from gene to obesity
Hong Wang,Robert H. Eckel +1 more
TL;DR: Overall, LPL is a fascinating enzyme that contributes in a pronounced way to normal lipoprotein metabolism, tissue-specific substrate delivery and utilization, and the many aspects of obesity and other metabolic disorders that relate to energy balance, insulin action, and body weight regulation.
Journal ArticleDOI
What are lipoproteins doing in the brain
Hong Wang,Robert H. Eckel +1 more
TL;DR: Understanding lipoproteins and their metabolism in the brain provides a new opportunity with potential therapeutic relevance in the regulation of body weight and energy balance.
Journal ArticleDOI
Deficiency of Lipoprotein Lipase in Neurons Modifies the Regulation of Energy Balance and Leads to Obesity
Hong Wang,Giuseppe Astarita,Matthew D. Taussig,Kalyani G. Bharadwaj,Nicholas V. DiPatrizio,Klaus-Armin Nave,Daniele Piomelli,Daniele Piomelli,Ira J. Goldberg,Robert H. Eckel +9 more
TL;DR: Results indicate that TG-rich lipoproteins are sensed in the brain by an LPL-dependent mechanism and provide lipid signals for the central regulation of body weight and energy balance.
Journal ArticleDOI
Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues
Hong Wang,Leslie A. Knaub,Dalan R. Jensen,Dae Young Jung,Eun-Gyoung Hong,Hwi Jin Ko,Alison M. Coates,Ira J. Goldberg,Becky A. de la Houssaye,Rachel C. Janssen,Carrie E. McCurdy,Shaikh M. Rahman,Cheol Soo Choi,Gerald I. Shulman,Jason K. Kim,Jacob E. Friedman,Robert H. Eckel +16 more
TL;DR: It is found that lack of LPL in skeletal muscle results in insulin resistance in other key metabolic tissues and ultimately leads to obesity and systemic insulin resistance.