H
Hossein Baharvand
Researcher at University of Science and Culture
Publications - 487
Citations - 20462
Hossein Baharvand is an academic researcher from University of Science and Culture. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 56, co-authored 454 publications receiving 15081 citations. Previous affiliations of Hossein Baharvand include Avicenna Research Institute & Royan Institute.
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Journal ArticleDOI
Enhanced development of mouse single blastomeres into blastocysts via the simultaneous inhibition of TGF-β and ERK pathways in microdroplet culture.
Farshid Yekani,Farshid Yekani,Mahnaz Azarnia,Fereshteh Esfandiari,Seyedeh-Nafiseh Hassani,Hossein Baharvand,Hossein Baharvand +6 more
TL;DR: It is found that BL development was improved in a lower volume of medium compared with a higher volume, and the supplementation of medium with the inhibitors of ERK1/2 and TGFβ signaling pathways in 1 µL droplets of T6 medium improved BL development.
Journal Article
Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors
Rokhsareh Meamar,F Karamali,Seyed Ali Reza Mousavi,Hossein Baharvand,Mohammad Hossein Nasr-Esfahani +4 more
TL;DR: A dual role for MDMA on mESCs: reduced proliferation and maintenance of self-renewal and the lack of decreasing stemness characteristic in presence of MPEP suggests that MDMA mediates its role through a different mechanism that requires further investigation.
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Hydrocortisone Promotes Differentiation of Mouse Embryonic Stem Cell-Derived Definitive Endoderm toward Lung Alveolar Epithelial Cells.
Mohammad Reza Mokhber Dezfouli,Sirous Sadeghian Chaleshtori,Azadeh Moradmand,Mohsen Basiri,Hossein Baharvand,Yaser Tahamtani +5 more
TL;DR: Results suggest that hydrocortisone can be a promoting factor in alveolar fate differentiation of IDE2- induced mESC-DE cells, which have potential for drug screening and cell-replacement therapies.
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Pan-cancer analysis of microRNA expression profiles highlights microRNAs enriched in normal body cells as effective suppressors of multiple tumor types: A study based on TCGA database
Sharif Moradi,Aryan Kamal,Hamidreza Aboulkheyr Es,Farnoosh Farhadi,Mansour Ebrahimi,Hamidreza Chitsaz,Ali Sharifi-Zarchi,Hossein Baharvand +7 more
TL;DR: A small set of tumour-suppressing miRNAs (which the authors designate as ’normomiRs’) are revealed that are highly expressed in 14 types of normal tissues but poorly expressed in corresponding tumour tissues and exert the most potent inhibition on multiple cancer types in vitro.
Journal Article
Assessment of potassium current in Royan B(1) stem cell derived cardiomyocytes by patch-clamp technique.
Hassan Sadraei,Seyed Reza Abtahi,M Nematollahi,Khadije Karbalaie,F Karamali,Hossein Baharvand,Mohammad Hossein Nasr-Esfahani +6 more
TL;DR: In the present study, functional large conductance Ca2+ activated K+ channel is identified in Royan B1 stem cell derived cardiomyocytes, indicating that voltageactivated K+ channels are developing in these cells but it is not yet fully functional.