H
Hossein Baharvand
Researcher at University of Science and Culture
Publications - 487
Citations - 20462
Hossein Baharvand is an academic researcher from University of Science and Culture. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 56, co-authored 454 publications receiving 15081 citations. Previous affiliations of Hossein Baharvand include Avicenna Research Institute & Royan Institute.
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Differential effect of activin on mouse embryonic stem cell differentiation in insulin-secreting cells under nestin-positive selection and spontaneous differentiation protocols
Hanieh Jafary,Bagher Larijani,Ali Farrokhi,Mehdi Pirouz,Sepideh Mollamohammadi,Hossein Baharvand +5 more
TL;DR: Significant insulin concentrations in protocol 1 were produced when glucose was added to the medium, in comparison with protocol 2, and improvements of the current method are required to generate a sufficient source of true beta‐cells for the treatment of diabetes mellitus.
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Cotransplantation of human embryonic stem cell-derived neural progenitors and schwann cells in a rat spinal cord contusion injury model elicits a distinct neurogenesis and functional recovery
Ali Niapour,Fereshteh Karamali,Shiva Nemati,Zahra Taghipour,Zahra Taghipour,Mohammad Mardani,Mohammad Hossein Nasr-Esfahani,Hossein Baharvand,Hossein Baharvand +8 more
TL;DR: It is demonstrated that the cotransplantation of SCs with hESC-NPs could offer a synergistic effect, promoting neuronal differentiation and functional recovery.
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Simultaneous Suppression of TGF-β and ERK Signaling Contributes to the Highly Efficient and Reproducible Generation of Mouse Embryonic Stem Cells from Previously Considered Refractory and Non-permissive Strains
Seyedeh-Nafiseh Hassani,Seyedeh-Nafiseh Hassani,Mehdi Totonchi,Mehdi Totonchi,Ali Farrokhi,Adeleh Taei,Mehran Rezaei Larijani,Hamid Gourabi,Hossein Baharvand,Hossein Baharvand +9 more
TL;DR: This study has identified dual inhibition of TGF-β and ERK1/2, by SB431542 and PD0325901, respectively, which led to the highly efficient and reproducible generation of mESC lines from NMRI, C57BL/6, BALB/c, DBA/ 2, and FVB/N strains, which previously were considered refractory or non-permissive for ESC establishment.
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Signaling Roadmap Modulating Naive and Primed Pluripotency
TL;DR: Accurate identification of the functions of major pluripotency-related signaling pathways and their cross-talk networks should aid in the successful induction of stable naive pluripotent states in human cells.
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Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7
Sahar Olsadat Sajadian,Chaturvedula Tripura,Fazel Sahraneshin Samani,Marc Ruoss,Steven Dooley,Hossein Baharvand,Andreas K. Nussler +6 more
TL;DR: It is shown for the first time in HCC that the combination of 5-AZA and vitamin C leads to an enhanced downregulation of Snail expression, a key transcription factor governing epithelial-mesenchymal transition (EMT) process, and cell cycle arrest.