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Howard N. Hodis

Researcher at University of Southern California

Publications -  318
Citations -  24700

Howard N. Hodis is an academic researcher from University of Southern California. The author has contributed to research in topics: Menopause & Intima-media thickness. The author has an hindex of 74, co-authored 297 publications receiving 22233 citations. Previous affiliations of Howard N. Hodis include Oklahoma Medical Research Foundation.

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Abstract 13283: Testing the Menopausal Hormone Therapy Timing Hypothesis: The Early versus Late Intervention Trial with Estradiol

TL;DR: The Early versus Late Intervention Trial with Estradiol is a 2x2, double-blinded, placebo-controlled trial specifically designed to determine whether menopausal hormone therapy (HT) has a differential effect on slowing the progression of subclinical atherosclerosis according to time-since-menopause when HT is initiated.
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17β-Estradiol reverses shear-stress-mediated low density lipoprotein modifications

TL;DR: In addition to upregulation of endothelial (.-)NO synthase and downregulation of Nox4 expression, E(2) influences LDL modifications via lipid peroxidation and protein nitration as determined by high-performance liquid chromatography.
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Antioxidants and atherosclerosis: an overview.

TL;DR: Support for the role of oxidants in the development of atherosclerosis also comes from recent clinical trials demonstrating antioxidant protection beyond that afforded by lipid lowering therapies, and the therapeutic potential of antioxidants can be demonstrated in many of the key steps described for early Atherosclerosis.
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Physical activity and sex hormone levels in estradiol- and placebo-treated postmenopausal women.

TL;DR: Physical activity is associated with lower serum levels of estradiol in both hormone therapy-treated and untreated women, and in placebo-treated women only, physical activity isassociated with reduced androgen levels and elevated SHBG levels.