Htet A. Khant

TL;DR: In this article, the authors describe interbilayer-crosslinked multilamellar vesicles formed by crosslinking headgroups of adjacent lipid bilayers within multilevel-vesicles, which can elicit endogenous T-cell and antibody responses comparable to those for the strongest vaccine vectors.

TL;DR: It is found that interbilayer-crosslinked multilamellar vesicles (ICMVs) form an extremely potent whole-protein vaccine, eliciting endogenous T-cell and antibody responses comparable to the strongest vaccine vectors.

TL;DR: This work reports the nanoscale loading and confinement of aquated Gd3+n-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes) that are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd 3+-based contrast agent (CA) in current clinical use.

TL;DR: It is shown that Ca2+ induces high-affinity simultaneous binding of synaptotagmin to two membranes, bringing them into close proximity and accelerates membrane fusion through the highly positive electrostatic potential of its C2B domain.

TL;DR: This model of mature Aβ1–42 fibrils is markedly different from previous cryoEM models of A β1–40 fibrILS, and the C terminus of Aβ forms the inside wall of the hollow core, which is supported by partial proteolysis analysis.