Xiangdong Wang

TL;DR: The goal of this article is to summarize and evaluate the results of experimental findings in LPS-induced ALI/ARDS, and the possible mechanisms and treatments elucidated, and disadvantages of such models in pulmonary research and new directions for future investigations are discussed.

TL;DR: A comprehensive picture of the HCC ecosystem provides deeper insights into immune evasion mechanisms associated with tumor relapse, including those that dampen DC antigen presentation and recruit innate-like CD8+ T cells.

TL;DR: The new concept of dynamical network biomarkers (DNBs) has been developed, which is different from traditional static approaches, and the DNB is able to distinguish a predisease state from normal and disease states by even a small number of samples, and therefore has great potential to achieve “real” early diagnosis of complex diseases.

TL;DR: It is reported that MLN4924 also triggers autophagy in response to CRL inactivation and that this effect is important for the ability of MLN 4924 to suppress the outgrowth of liver cancer cells in vitro and in vivo.

TL;DR: Recent advances in investigating the roles of autophagy in inflammation as well as inflammatory diseases are highlighted.