Hugh Middleton

TL;DR: The results suggest that decision making recruits neural activity from multiple regions of the inferior PFC that receive information from a diverse set of cortical and limbic inputs, and that the contribution of the orbitofrontal regions may involve processing changes in reward-related information.

TL;DR: C cognitive therapy was superior to both applied relaxation and imipramine on most measures and self-exposure homework assignments taken at the end of treatment were significant predictors of outcome at follow-up.

TL;DR: In this paper, the authors argue that good practice in psychiatry primarily involves engagement with the non-technical dimensions of our work such as relationships, meanings and values, and that particular skills are needed to practice a "medicine of the mind".

TL;DR: Reduction in central serotonin leads to altered neuromodulation of the cortical and subcortical regions (e.g. orbitofrontal cortex, striatum and anterior temporal structures) that mediate important aspects of associative learning whereby exteroceptive stimuli acquire altered incentive motivational value.

TL;DR: This paper provided a brief overview of one of the theories described by Clark (1986) and described a series of experiments testing central predictions derived from this theory, which can also account for the main features of panic.