H
Hui-Jun Lu
Researcher at China Mobile
Publications - 7
Citations - 435
Hui-Jun Lu is an academic researcher from China Mobile. The author has contributed to research in topics: Sierra leone & Ebola virus. The author has an hindex of 6, co-authored 7 publications receiving 379 citations.
Papers
More filters
Journal ArticleDOI
Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Yigang Tong,Weifeng Shi,Di Liu,Jun Qian,Long Liang,Xiaochen Bo,Jun Liu,Hong-Guang Ren,Hang Fan,Ming Ni,Yang Sun,Yuan Jin,Yue Teng,Zhen Li,David Kargbo,Foday Dafae,Alex Kanu,Cheng-Chao Chen,Zhi-Heng Lan,Hui Jiang,Yang Luo,Hui-Jun Lu,Xiao-Guang Zhang,Fan Yang,Yi Hu,Yuxi Cao,Yong-Qiang Deng,Haoxiang Su,Yu Sun,Liu Wensen,Zhuang Wang,Cheng-Yu Wang,Zhao-Yang Bu,Zhen-Dong Guo,Liu-Bo Zhang,Wei-Min Nie,Changqing Bai,Chun-Hua Sun,Xiaoping An,Peisong Xu,Xianglilan Zhang,Yong Huang,Zhiqiang Mi,Dong Yu,Hong-Wu Yao,Yong Feng,Zhiping Xia,Xuexing Zheng,Songtao Yang,Bing Lu,Jia-Fu Jiang,Brima Kargbo,Fu-Chu He,George F. Gao,Wu-Chun Cao +54 more
TL;DR: The 2014 Ebola virus has become more phylogenetically and genetically diverse from July to November 2014, characterized by the emergence of multiple novel lineages and the sharp increase in genetic diversity of the 2014 EBOV.
Journal ArticleDOI
Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated with favipiravir (T-705), Sierra Leone, 2014
Changqing Bai,Jin-Song Mu,David Kargbo,Ya-Bin Song,Wenkai Niu,Wei-Min Nie,Alex Kanu,Wei-Wei Liu,Yao-Ping Wang,Foday Dafae,Tao Yan,Yi Hu,Yong-Qiang Deng,Hui-Jun Lu,Fan Yang,Xiao-Guang Zhang,Yang Sun,Yuxi Cao,Haoxiang Su,Yu Sun,Liu Wensen,Cheng-Yu Wang,Jun Qian,Liu Liu,Hong Wang,Yigang Tong,Ze-Yuan Liu,Yun-Song Chen,Hong-Quan Wang,Brima Kargbo,George F. Gao,Jia-Fu Jiang +31 more
TL;DR: Treatment of EVD with T-705 was associated with prolonged survival and markedly reduced viral load, which makes a compelling case for further randomized controlled trials of T-707 for treating EVD.
Journal ArticleDOI
Intra-host dynamics of Ebola virus during 2014.
Ming Ni,Chen Chen,Jun Qian,Haixia Xiao,Weifeng Shi,Yang Luo,Hai-Yin Wang,Zhen Li,Jun Wu,Peisong Xu,Su-Hong Chen,Gary Wong,Yuhai Bi,Zhiping Xia,Wei Li,Hui-Jun Lu,Juncai Ma,Yigang Tong,Hui Zeng,Shengqi Wang,George F. Gao,George F. Gao,Xiaochen Bo,Di Liu +23 more
TL;DR: A comprehensive distribution of iSNVs during this outbreak and along the EBOV genome is presented and it is revealed that VP40 is the most conserved gene during this outbreaks and thus it would be an ideal therapeutic target.
Journal ArticleDOI
Ebola Virus Outbreak Investigation, Sierra Leone, September 28-November 11, 2014.
Hui-Jun Lu,Jun Qian,David Kargbo,Xiao-Guang Zhang,Fan Yang,Yi Hu,Yang Sun,Yuxi Cao,Yong-Qiang Deng,Haoxiang Su,Foday Dafae,Yu Sun,Cheng-Yu Wang,Wei-Min Nie,Changqing Bai,Zhiping Xia,Kun Liu,Brima Kargbo,George F. Gao,Jia-Fu Jiang +19 more
TL;DR: Knowledge of epidemiologic, clinical, and viral features of the outbreak is critical for optimizing control and treatment measures.
Journal ArticleDOI
Rapid deployment of a mobile biosafety level-3 laboratory in Sierra Leone during the 2014 Ebola virus epidemic.
Yi Zhang,Yan Gong,Wang Chengyu,Liu Wensen,Zhongyi Wang,Zhiping Xia,Bu Zhaoyang,Hui-Jun Lu,Yang Sun,Xiaoguang Zhang,Yuxi Cao,Fan Yang,Haoxiang Su,Yi Hu,Yong-Qiang Deng,Bo Zhou,Zongzheng Zhao,Yingying Fu,David Kargbo,Foday Dafae,Brima Kargbo,Alex Kanu,Linna Liu,Jun Qian,Zhendong Guo +24 more
TL;DR: The China mobile laboratory was instrumental in the EVD outbreak response by providing timely and reliable diagnostics and significantly contributed to establishing a suitable laboratory response capacity during the emergence of EVD in Sierra Leone.