H
Huib N. Caron
Researcher at University of Amsterdam
Publications - 74
Citations - 10178
Huib N. Caron is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Neuroblastoma & Gene. The author has an hindex of 41, co-authored 72 publications receiving 9388 citations. Previous affiliations of Huib N. Caron include Boston Children's Hospital.
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Journal ArticleDOI
Clinical heart failure during pregnancy and delivery in a cohort of female childhood cancer survivors treated with anthracyclines.
Elvira C. van Dalen,Helena J.H. van der Pal,Cor van den Bos,Wouter E.M. Kok,Huib N. Caron,Leontien C. M. Kremer +5 more
TL;DR: In this article, the cumulative incidence of peripartum anthracycline-induced clinical heart failure (A-CHF) was evaluated in a cohort of 53 childhood cancer survivors who had delivered one or more children.
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Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression
TL;DR: It is concluded that most neuroblastoma cell lines are sensitive to YM155 in the low nM range and that resistant cells can be sensitised by ABCB1 inhibitors.
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Fenretinide induces mitochondrial ROS and inhibits the mitochondrial respiratory chain in neuroblastoma
TL;DR: The cytotoxicity of fenretinide was exerted through the generation of mitochondrial ROS and, at higher concentrations, also through inhibition of the mitochondrial respiratory chain.
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Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours
Laurel T. Bate-Eya,Marli E. Ebus,Jan Koster,Ilona J.M. den Hartog,Danny A. Zwijnenburg,Linda Schild,Ida van der Ploeg,M. Emmy M. Dolman,Huib N. Caron,Rogier Versteeg,Jan J. Molenaar +10 more
TL;DR: Investigating the growth characteristics and confirmed tumour-forming potential of eight newly-derived neuroblastoma TICs cultured under serum-free conditions establish that they are relevant and useful Neuroblastoma tumour models.
Journal Article
Development of a real-time polymerase chain reaction assay for prediction of the uptake of meta-[(131)I]iodobenzylguanidine by neuroblastoma tumors.
Sean Carlin,Robert J. Mairs,Anthony G. McCluskey,Deborah A. Tweddle,Alan Sprigg,Christine Estlin,Julian Board,Rani E. George,C. Ellershaw,Andrew D.J. Pearson,John Lunec,Paolo G. Montaldo,Mirco Ponzoni,Berthe L. F. van Eck-Smit,Cees A. Hoefnagel,Marieke Dekker van den Brug,Godelieve A.M. Tytgat,Huib N. Caron +17 more
TL;DR: In this paper, the suitability of neuroblastoma patients for therapy using radiolabeled meta-iodobenzylguanidine (MIBG) is determined by scintigraphy after the administration of a tracer dose of radioiodinated MIBG whose uptake is dependent upon the cellular expression of the noradrenaline transporter (NAT).