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Huilian Zhu
Researcher at Sun Yat-sen University
Publications - 75
Citations - 2197
Huilian Zhu is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 56 publications receiving 1547 citations.
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Journal ArticleDOI
Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults
Yu-ming Chen,Yan Liu,Rui-fen Zhou,Xiao-ling Chen,Cheng Wang,Xuying Tan,Lijun Wang,Rui-dan Zheng,Hong-wei Zhang,Wenhua Ling,Huilian Zhu +10 more
TL;DR: The findings showed adverse associations between the circulating TMAO level and the presence and severity of NAFLD in hospital- and community-based Chinese adults, and a favorable betaine-NAFLD relationship in the community- based participants.
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An Anthocyanin-Rich Extract from Black Rice Enhances Atherosclerotic Plaque Stabilization in Apolipoprotein E–Deficient Mice
TL;DR: Chronic diet intake of anthocyanin-rich extract from black rice may enhance plaque stabilization in old apoE-deficient mice, and the underlying mechanism is related to inhibiting proinflammatory factors and improving the serum lipid profile.
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Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China.
Hani El-Nezami,Nektaria Polychronaki,Jing Ma,Huilian Zhu,Wenhua Ling,Eeva Salminen,Risto O. Juvonen,Seppo Salminen,Tuija Poussa,Hannu Mykkänen +9 more
TL;DR: A probiotic supplement reduces the biologically effective dose of aflatoxin exposure and may thereby offer an effective dietary approach to decrease the risk of liver cancer.
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Anthocyanins Induce Cholesterol Efflux from Mouse Peritoneal Macrophages THE ROLE OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ-LIVER X RECEPTOR α-ABCA1 PATHWAY
Min Xia,Mengjun Hou,Huilian Zhu,Jing Ma,Zhihong Tang,Qing Wang,Yan Li,Dong-sheng Chi,Xiao-ping Yu,Ting Zhao,Pinghua Han,Xiaodong Xia,Wenhua Ling +12 more
TL;DR: It is demonstrated that anthocyanin induces cholesterol efflux from mouse peritoneal macrophages and macrophage-derived foam cells and that stimulation ofolesterol efflux by anthocianin is mediated, at least in part, by peroxisome proliferator-activated receptor γ-liver X receptor α-ABCA1 signaling pathway activation.
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Trimethylamine N‐Oxide Aggravates Liver Steatosis through Modulation of Bile Acid Metabolism and Inhibition of Farnesoid X Receptor Signaling in Nonalcoholic Fatty Liver Disease
Xuying Tan,Yan Liu,Jing-An Long,Si Chen,Gong-Cheng Liao,Shang-Ling Wu,Chun-lei Li,Lijun Wang,Wenhua Ling,Huilian Zhu +9 more
TL;DR: TMAO aggravates liver steatosis by suppressing BA-mediated hepatic FXR signaling and increases BA synthesis and shifted hepatic BA composition toward FXR-antagonistic activity.