M
Mengjun Hou
Researcher at Sun Yat-sen University
Publications - 23
Citations - 1038
Mengjun Hou is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Proinflammatory cytokine & Tumor necrosis factor alpha. The author has an hindex of 13, co-authored 22 publications receiving 973 citations.
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Journal ArticleDOI
An Anthocyanin-Rich Extract from Black Rice Enhances Atherosclerotic Plaque Stabilization in Apolipoprotein E–Deficient Mice
TL;DR: Chronic diet intake of anthocyanin-rich extract from black rice may enhance plaque stabilization in old apoE-deficient mice, and the underlying mechanism is related to inhibiting proinflammatory factors and improving the serum lipid profile.
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Anthocyanins Induce Cholesterol Efflux from Mouse Peritoneal Macrophages THE ROLE OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ-LIVER X RECEPTOR α-ABCA1 PATHWAY
Min Xia,Mengjun Hou,Huilian Zhu,Jing Ma,Zhihong Tang,Qing Wang,Yan Li,Dong-sheng Chi,Xiao-ping Yu,Ting Zhao,Pinghua Han,Xiaodong Xia,Wenhua Ling +12 more
TL;DR: It is demonstrated that anthocyanin induces cholesterol efflux from mouse peritoneal macrophages and macrophage-derived foam cells and that stimulation ofolesterol efflux by anthocianin is mediated, at least in part, by peroxisome proliferator-activated receptor γ-liver X receptor α-ABCA1 signaling pathway activation.
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Cyanidin-3-O-beta-glucoside inhibits iNOS and COX-2 expression by inducing liver X receptor alpha activation in THP-1 macrophages.
Qing Wang,Min Xia,Chi Liu,Honghui Guo,Qingyuan Ye,Yan Hu,Yinghui Zhang,Mengjun Hou,Huilian Zhu,Jing Ma,Wenhua Ling +10 more
TL;DR: Results indicate that LXRalpha activation has an essential role in the anti-inflammatory property of C3G, and provide new insight into the molecular basis for theAnti-inflammatory properties of anthocyanins.
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Anthocyanin Prevents CD40-Activated Proinflammatory Signaling in Endothelial Cells by Regulating Cholesterol Distribution
Min Xia,Wenhua Ling,Huilian Zhu,Qing Wang,Jing Ma,Mengjun Hou,Zhihong Tang,Lan Li,Qinyuan Ye +8 more
TL;DR: The findings suggest that anthocyanin protects from CD40-induced proinflammatory signaling by preventing TRAF-2 translocation to lipid rafts through regulation of cholesterol distribution, which thereby may represent a mechanism that would explain the anti-inflammatory response of anthcyanin.
Journal ArticleDOI
Supplementation of black rice pigment fraction improves antioxidant and anti-inflammatory status in patients with coronary heart disease.
Qing Wang,Pinghua Han,Mingwei Zhang,Min Xia,Hui-lian Zhu,Jing Ma,Mengjun Hou,Zhihong Tang,Wenhua Ling +8 more
TL;DR: The results may suggest that BRF could exert cardioprotective effects on patients with CHD by improving plasma antioxidant status and inhibiting inflammatory factors.