H
Hunter C. Champion
Researcher at Johns Hopkins University
Publications - 275
Citations - 23191
Hunter C. Champion is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Pulmonary hypertension & Adrenomedullin. The author has an hindex of 74, co-authored 275 publications receiving 21959 citations. Previous affiliations of Hunter C. Champion include Johns Hopkins University School of Medicine & National Institutes of Health.
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Journal ArticleDOI
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
Ilan S. Wittstein,David R. Thiemann,Joao A.C. Lima,Kenneth L. Baughman,Steven P. Schulman,Gary Gerstenblith,Katherine C. Wu,Jeffrey J. Rade,Trinity J. Bivalacqua,Hunter C. Champion +9 more
TL;DR: Emotional stress can precipitate severe, reversible left ventricular dysfunction in patients without coronary disease andaggerated sympathetic stimulation is probably central to the cause of this syndrome.
Journal ArticleDOI
Diagnosis and Assessment of Pulmonary Arterial Hypertension
David B. Badesch,Hunter C. Champion,Miguel Angel Gomez Sanchez,Marius M. Hoeper,James E. Loyd,Alessandra Manes,Michael D. McGoon,Robert Naeije,Horst Olschewski,Ronald J. Oudiz,Adam Torbicki +10 more
TL;DR: A clear definition of pulmonary hypertension and the development of a rational approach to diagnostic assessment and follow-up using both conventional and new tools will be essential to deriving maximal benefit from the expanding therapeutic armamentarium.
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Tricuspid annular displacement predicts survival in pulmonary hypertension.
Paul R. Forfia,Micah R. Fisher,Stephen C. Mathai,Traci Housten-Harris,Anna R. Hemnes,Barry A. Borlaug,Elzbieta Chamera,Mary C. Corretti,Hunter C. Champion,Theodore P. Abraham,Reda E. Girgis,Paul M. Hassoun +11 more
TL;DR: TAPSE powerfully reflects RV function and prognosis in PAH and persisted after adjusting for other echocardiographic and hemodynamic variables and baseline treatment status.
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Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension.
Micah R. Fisher,Paul R. Forfia,Paul R. Forfia,Elzbieta Chamera,Traci Housten-Harris,Hunter C. Champion,Reda E. Girgis,Mary C. Corretti,Paul M. Hassoun +8 more
TL;DR: Doppler echocardiography may frequently be inaccurate in estimating pulmonary artery pressure and cardiac output in patients being evaluated for PH, according to a prospective study on patients with various forms of PH.
Journal ArticleDOI
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
Eiki Takimoto,Hunter C. Champion,Manxiang Li,Diego F. Belardi,Shuxun Ren,E. Rene Rodriguez,Djahida Bedja,Kathleen L. Gabrielson,Yibin Wang,David A. Kass +9 more
TL;DR: It is shown that blocking the intrinsic catabolism of cGMP with an oral phosphodiesterase-5A (PDE5A) inhibitor (sildenafil) suppresses chamber and myocyte hypertrophy, and improves in vivo heart function in mice exposed to chronic pressure overload induced by transverse aortic constriction.