H
Hunter C. Champion
Researcher at Johns Hopkins University
Publications - 275
Citations - 23191
Hunter C. Champion is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Pulmonary hypertension & Adrenomedullin. The author has an hindex of 74, co-authored 275 publications receiving 21959 citations. Previous affiliations of Hunter C. Champion include Johns Hopkins University School of Medicine & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Vasodilator responses to the endomorphin peptides, but not nociceptin/OFQ, are mediated by nitric oxide release.
Hunter C. Champion,Trinity J. Bivalacqua,James E. Zadina,James E. Zadina,Abba J. Kastin,Abba J. Kastin,Philip J. Kadowitz +6 more
TL;DR: Endomorphin peptides, endogenous ligands for the μ‐opioid receptor, and nociceptin (orphanin FQ; OFQ), an endogenous ligand for the ORL1 receptor, have substantial vasodilator activity in the rat and responses to these peptides are mediated in large part by the release of nitric oxide.
Journal ArticleDOI
R-(−)-α-methyl-histamine has nitric oxide-mediated vasodilator activity in the mesenteric vascular bed of the cat
TL;DR: The present data suggest that histamine H3 receptors mediating vasodilation are present in the mesenteric vascular bed and that responses are mediated by the release of nitric oxide but not vasodilator prostaglandins or an effect on the adrenergic nervous system.
Journal ArticleDOI
1202: Long-Term Phosphodiesterase Type 5 Inhibitor Therapy Reduces Priapic Activity in Transgenic Sickle Cell Mice
Journal ArticleDOI
Analysis of responses to kallidin, DABK, and DAK in feline hindlimb vascular bed
TL;DR: Results suggest that kinin B1 and B2 receptor-mediated vasodilator responses are mediated by the release of nitric oxide and that the activation of K+ATP channels or muscarinic receptors play little if any role in mediating responses to kallidin, DABK, or DAK in the hindlimb vascular bed of the cat.
Journal ArticleDOI
Feline penile erection induced by transurethral administration of sodium nitroprusside.
Trinity J. Bivalacqua,Hunter C. Champion,Run Wang,Philip J. Kadowitz,Paul C. Doherty,Wayne J.G. Hellstrom +5 more
TL;DR: The data suggest that transurethral administration of SNP can induce an erectile response in cats with minimal side effects, and Nitric oxide is an important mediator in the relaxation of cavernosal smooth muscle.