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Ian B. Hogue
Researcher at Arizona State University
Publications - 34
Citations - 4226
Ian B. Hogue is an academic researcher from Arizona State University. The author has contributed to research in topics: Virus & Biology. The author has an hindex of 18, co-authored 29 publications receiving 3521 citations. Previous affiliations of Ian B. Hogue include University of Michigan & University of Texas Southwestern Medical Center.
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A Methodology For Performing Global Uncertainty And Sensitivity Analysis In Systems Biology
TL;DR: This work develops methods for applying existing analytical tools to perform analyses on a variety of mathematical and computer models and provides a complete methodology for performing these analyses, in both deterministic and stochastic settings, and proposes novel techniques to handle problems encountered during these types of analyses.
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Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
Ginger Lehrman,Ian B. Hogue,Sarah Palmer,Cheryl Jennings,Celsa A. Spina,Ann Wiegand,Alan L. Landay,Robert W. Coombs,Douglas D. Richman,John W. Mellors,John M. Coffin,Ronald J. Bosch,David M. Margolis +12 more
TL;DR: In this article, the ability of the histone deacetylase 1 (HDAC) inhibitor valproic acid to deplete persistent, latent infection in resting CD4+ T cells was evaluated.
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Virus Infections in the Nervous System
TL;DR: How viruses gain access to and spread in the well-protected CNS is reviewed, with particular emphasis on alpha herpesviruses, which establish and maintain persistent NS infections.
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Interaction between the Human Immunodeficiency Virus Type 1 Gag Matrix Domain and Phosphatidylinositol-(4,5)-Bisphosphate Is Essential for Efficient Gag Membrane Binding
TL;DR: Results indicate that HIV-1 Gag binds PI(4,5)P2 on the membrane and that the MA basic domain mediates this interaction.
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3D printed nervous system on a chip
Blake N. Johnson,Blake N. Johnson,Karen Z. Lancaster,Ian B. Hogue,Fanben Meng,Fanben Meng,Yong Lin Kong,Lynn W. Enquist,Michael C. McAlpine,Michael C. McAlpine +9 more
TL;DR: It is found that Schwann cells participate in axon-to-cell viral spread but appear refractory to infection, exhibiting a multiplicity of infection (MOI) of 1.4 genomes per cell.