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Ibrahim M. Ibrahim

Researcher at Cairo University

Publications -  68
Citations -  1453

Ibrahim M. Ibrahim is an academic researcher from Cairo University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 10, co-authored 26 publications receiving 749 citations.

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COVID-19 spike-host cell receptor GRP78 binding site prediction

TL;DR: The COVID-19 spike binding site to the cell-surface receptor (Glucose Regulated Protein 78 (GRP78) is predicted using combined molecular modeling docking and structural bioinformatics and sequence and structural alignments show that four regions have sequence and physicochemical similarities to the cyclic Pep42.
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GRP78: A cell's response to stress

TL;DR: The present review summarizes structure, function, and different mechanisms GRP78 mediate in response to normal or stress conditions aiming to prevent the virulence of pathogens and cancer.
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Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin-induced Type 1 diabetes.

TL;DR: It is concluded that Vitamin E supplementation in addition to insulin can have additive protective effects against deterioration of renal function in this model of diabetes and ROS may play an important role in diabetes-induced nephropathy.
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Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19.

TL;DR: This study will hopefully pave a way for development of phytonutrients-based antiviral therapeutic for treatment or prevention of COVID-19 and further studies are recommended to evaluate the antiviral effects of these phytochemicals against SARS-CoV-2 in in vitro and in vivo models.
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Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis.

TL;DR: The study suggests the feasibility of applying the gold nanorods-PPTT on natural tumors in dogs and cats without any relapse or toxicity effects after 1 year of treatment.