M
Micheal C. Wilson
Researcher at University of California, San Diego
Publications - 11
Citations - 1422
Micheal C. Wilson is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Polyketide synthase & Polyketide. The author has an hindex of 10, co-authored 11 publications receiving 1232 citations. Previous affiliations of Micheal C. Wilson include University of Bonn & ETH Zurich.
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Journal ArticleDOI
An environmental bacterial taxon with a large and distinct metabolic repertoire
Micheal C. Wilson,Tetsushi Mori,Christian Rückert,Agustinus Robert Uria,Maximilian J. Helf,Maximilian J. Helf,Kentaro Takada,Christine Gernert,Ursula A. E. Steffens,Nina Heycke,Susanne Schmitt,Christian Rinke,Eric J. N. Helfrich,Eric J. N. Helfrich,Alexander O. Brachmann,Cristian Gurgui,Toshiyuki Wakimoto,Matthias Kracht,Max Crüsemann,Ute Hentschel,Ikuro Abe,Shigeki Matsunaga,Jörn Kalinowski,Haruko Takeyama,Jörn Piel,Jörn Piel +25 more
TL;DR: Two phylotypes of the candidate genus ‘Entotheonella’ with genomes of greater than 9 megabases and multiple, distinct biosynthetic gene clusters co-inhabit the chemically and microbially rich marine sponge Theonella swinhoei.
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Genomes of coral dinoflagellate symbionts highlight evolutionary adaptations conducive to a symbiotic lifestyle
Manuel Aranda,Yangyang Li,Yi Jin Liew,Sebastian Baumgarten,Oleg Simakov,Micheal C. Wilson,Jörn Piel,Haitham Ashoor,Salim Bougouffa,Vladimir B. Bajic,Taewoo Ryu,Timothy Ravasi,Till Bayer,Till Bayer,Gos Micklem,Hak-Min Kim,Jong Bhak,Todd C. LaJeunesse,Christian R. Voolstra +18 more
TL;DR: Comparative analyses of genome and transcriptome protein sets show that all dinoflagellates, not only Symbiodinium, possess significantly more transmembrane transporters involved in the exchange of amino acids, lipids, and glycerol than other eukaryotes.
Journal ArticleDOI
Metagenomic Approaches for Exploiting Uncultivated Bacteria as a Resource for Novel Biosynthetic Enzymology
Micheal C. Wilson,Jörn Piel +1 more
TL;DR: This perspective highlights recent discoveries from metagenomics of uncultivated bacteria and discusses the impact of those findings on the field of natural products.
Journal ArticleDOI
Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity.
TL;DR: This review covers the emerging biosynthetic role of crotonyl-CoA carboxylase/reductase (CCR) homologs in extending the structural and functional diversity of polyketide natural products.
Journal ArticleDOI
Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.
Daniel W. Udwary,Erin A. Gontang,Adam C. Jones,Carla S. Jones,Andrew W. Schultz,Jaclyn M. Winter,Jane Y. Yang,Nicholas Beauchemin,Todd L. Capson,Benjamin R. Clark,Eduardo Esquenazi,Alessandra S. Eustáquio,Kelle C. Freel,Lena Gerwick,William H. Gerwick,William H. Gerwick,David Gonzalez,Wei-Ting Liu,Karla L. Malloy,Katherine N. Maloney,Markus Nett,Joshawna K. Nunnery,Kevin Penn,Alejandra Prieto-Davó,Thomas L. Simmons,Sara Weitz,Micheal C. Wilson,Louis S. Tisa,Pieter C. Dorrestein,Pieter C. Dorrestein,Bradley S. Moore,Bradley S. Moore +31 more
TL;DR: Bioinformatic analysis of the genome sequences of Frankia strains ACN14a, CcI3, and EAN1pec revealed an unexpected number of secondary metabolic biosynthesis gene clusters, demonstrating species-specific biosynthetic diversity and presenting a clear roadmap for natural products discovery in the Frankia genus.