Ilana Ariel

TL;DR: The group agreed on sets of uniform sampling criteria, placental gross descriptors, pathologic terminologies, and diagnostic criteria for placental lesions, which will assist in international comparability of clinicopathologic and scientific studies and assist in refining the significance of lesions associated with adverse pregnancy and later health outcomes.

TL;DR: It is proposed that this combined group of villous lesions be dichotomized with the terms fetal thrombotic vasculopathy or extensive avascular villi (and/or villous stromal-vascular karyorrhexis) being reserved for the group with 15 or more affected terminal villi per section.

TL;DR: It is proposed that trophoblasts lacking HLA-G are vulnerable to attack by the maternal immune system and will be unable to invade the maternal spiral arteries effectively, thereby developing vessels which cannot adequately nourish the developing placenta.

TL;DR: Using a unique human tissue, the androgenetic complete hydatidiform mole, it is established that the maternally inherited allele of the imprinted H19 gene is expressed and that the paternal allele ofthe human IGF‐II gene, a gene suspected to be parentally imprinted in humans, is expressed.

TL;DR: It might be possible to use H19 as a prognostic tumour marker for the early recurrence of bladder cancer and for the gene therapy of bladder carcinoma that is based on the transcriptional regulatory sequences of H19, the expression in an individual biopsy could be considered a predictive tumours marker for selecting those patients who would benefit from this form of treatment.