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Ilaria Penna
Researcher at Istituto Italiano di Tecnologia
Publications - 18
Citations - 614
Ilaria Penna is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Acid Ceramidase & Alternative splicing. The author has an hindex of 11, co-authored 18 publications receiving 471 citations. Previous affiliations of Ilaria Penna include University of Genoa & National Cancer Research Institute.
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An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples
Eleonora Ciarlo,Sara Massone,Ilaria Penna,Mario Nizzari,Arianna Gigoni,Giorgio Dieci,Claudio Russo,Tullio Florio,Ranieri Cancedda,Aldo Pagano +9 more
TL;DR: 51A expression drives a splicing shift of SORL1 from the synthesis of the canonical long protein variant A to an alternatively spliced protein form, which is associated with impaired processing of amyloid precursor protein (APP), leading to increased Aβ formation.
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A biocompatible sodium alginate/povidone iodine film enhances wound healing
Maria Summa,Debora Russo,Ilaria Penna,Natasha Margaroli,Ilker S. Bayer,Tiziano Bandiera,Athanassia Athanassiou,Rosalia Bertorelli +7 more
TL;DR: It is demonstrated that the NaAlg/PVPI films are biocompatible and possess healing properties that accelerate the wound closure, and are able to reduce the inflammatory response both in human foreskin fibroblasts after lipopolysaccharide stimulus and in rodents after wound induction.
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Selection of Candidate Housekeeping Genes for Normalization in Human Postmortem Brain Samples
TL;DR: The aim of this study is to identify the most stable genes in postmortem human brain samples of patients affected by Alzheimer’s disease suitable as reference genes and it is found that CYC1 and EIF4A2 are the best reference genes.
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Polyvinylpyrrolidone/hyaluronic acid-based bilayer constructs for sequential delivery of cutaneous antiseptic and antibiotic
Marco Contardi,Marco Contardi,Debora Russo,Giulia Suarato,José A. Heredia-Guerrero,Luca Ceseracciu,Ilaria Penna,Natasha Margaroli,Maria Summa,Raffaele Spanò,Giovanni Tassistro,Luigi Vezzulli,Tiziano Bandiera,Rosalia Bertorelli,Athanassia Athanassiou,Ilker S. Bayer +15 more
TL;DR: In this paper, a transparent bilayer construct for the sequential release and delivery of a cutaneous antiseptic and a widely used antibiotic, potentially suitable for wound dressing applications, is described.
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Towards combinatorial targeted therapy in melanoma: From pre-clinical evidence to clinical application (Review)
TL;DR: The anti-melanoma efficacy and mechanism of action of the above-mentioned combinatorial strategies are reviewed, together with the potential clinical application of the most promising studies that may eventually lead to therapeutic benefit.