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Iman K. Yazdi
Researcher at Brigham and Women's Hospital
Publications - 52
Citations - 2938
Iman K. Yazdi is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Drug delivery & Controlled release. The author has an hindex of 19, co-authored 50 publications receiving 2203 citations. Previous affiliations of Iman K. Yazdi include University of Texas Health Science Center at Houston & Massachusetts Institute of Technology.
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Journal ArticleDOI
Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions
Alessandro Parodi,Nicoletta Quattrocchi,Nicoletta Quattrocchi,Anne L. van de Ven,Ciro Chiappini,Michael Evangelopoulos,Jonathan O. Martinez,Jonathan O. Martinez,Brandon S. Brown,Brandon S. Brown,Sm Z. Khaled,Iman K. Yazdi,Iman K. Yazdi,Maria Vittoria Enzo,Maria Vittoria Enzo,Lucas Isenhart,Mauro Ferrari,Ennio Tasciotti +17 more
TL;DR: It is shown that nanoporous silicon particles can successfully perform all actions when they are coated with cellular membranes purified from leukocytes, and leukolike vectors retained their functions when injected in vivo, showing enhanced circulation time and improved accumulation in a tumour.
Journal ArticleDOI
Biomimetic proteolipid vesicles for targeting inflamed tissues
Roberto Molinaro,Claudia Corbo,Jonathan O. Martinez,Francesca Taraballi,Michael Evangelopoulos,Silvia Minardi,Iman K. Yazdi,Picheng Zhao,E. De Rosa,Michael B. Sherman,A. De Vita,N. E. Toledano Furman,Xin Wang,Alessandro Parodi,Ennio Tasciotti +14 more
TL;DR: A method is described that leverages the advantages of bottom-up and top-down strategies to incorporate proteins derived from the leukocyte plasma membrane into lipid nanoparticles that retained the versatility and physicochemical properties typical of liposomal formulations and enabled the selective and effective delivery of dexamethasone to inflamed tissues.
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Smart Bandage for Monitoring and Treatment of Chronic Wounds.
Pooria Mostafalu,Pooria Mostafalu,Pooria Mostafalu,Ali Tamayol,Rahim Rahimi,Manuel Ochoa,Akbar Khalilpour,Akbar Khalilpour,Gita Kiaee,Gita Kiaee,Iman K. Yazdi,Iman K. Yazdi,Sara Bagherifard,Sara Bagherifard,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Babak Ziaie,Sameer Sonkusale,Ali Khademhosseini +18 more
TL;DR: A smart and automated flexible wound dressing with temperature and pH sensors integrated onto flexible bandages that monitor wound status in real-time to address unmet medical need and has the potential to significantly impact the treatment of chronic wounds.
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Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix
Alessandro Parodi,Seth G. Haddix,Nima Taghipour,Shilpa Scaria,Francesca Taraballi,Armando Cevenini,Iman K. Yazdi,Claudia Corbo,Roberto Palomba,Sm Z. Khaled,Jonathan O. Martinez,Brandon S. Brown,Lucas Isenhart,Ennio Tasciotti +13 more
TL;DR: A simple method to provide mesoporous silica nanoparticles (MSN) with a proteolytic surface was developed, which increased particle uptake in endothelial, macrophage, and cancer cell lines with minimal impact on cellular viability and showed an increased ability to digest and diffuse in tumor ECM in vitro and in vivo.
Journal ArticleDOI
Adult and umbilical cord blood-derived platelet-rich plasma for mesenchymal stem cell proliferation, chemotaxis, and cryo-preservation
Matthew B. Murphy,Daniel Blashki,Rachel M. Buchanan,Rachel M. Buchanan,Iman K. Yazdi,Iman K. Yazdi,Mauro Ferrari,Paul J. Simmons,Ennio Tasciotti +8 more
TL;DR: It is demonstrated that PRP and PPP represented a viable alternative to FBS containing media for the cryo-preservation of MSC from human and rat BM and ucPRP showed greater potency than adult PRP, PPP from either source, or indeed than combinations of either recombinant growth factors or chemokines previously shown to stimulate chemotactic migration of M SC.