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Ina Theofel
Researcher at University of Marburg
Publications - 8
Citations - 85
Ina Theofel is an academic researcher from University of Marburg. The author has contributed to research in topics: Chromatin & Gene. The author has an hindex of 5, co-authored 8 publications receiving 60 citations.
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Journal ArticleDOI
Prtl99C Acts Together with Protamines and Safeguards Male Fertility in Drosophila
TL;DR: Data reveal that at least three chromatin-binding proteins act together in chromatin reorganization to compact the paternal chromatin, in agreement with independent loading of these factors into sperm chromatin.
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The HMG-box-containing proteins tHMG-1 and tHMG-2 interact during the histone-to-protamine transition in Drosophila spermatogenesis.
Stefanie M. K. Gärtner,Silke Rothenbusch,Melanie K. Buxa,Ina Theofel,Rainer Renkawitz,Christina Rathke,Renate Renkawitz-Pohl +6 more
TL;DR: In this article, the authors showed that the transition-protein-like protein Tpl94D contains an HMG-box domain and is expressed during chromatin reorganization, which is associated with a remarkable reorganization of the chromatin in post-meiotic stages.
Journal ArticleDOI
tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family.
Ina Theofel,Marek Bartkuhn,Tim Hundertmark,Thomas Boettger,Stefanie M. K. Gärtner,Katja Leser,Stephan Awe,Michael Schipper,Renate Renkawitz-Pohl,Christina Rathke +9 more
TL;DR: Comparing the transcriptomes of tbrd-1 mutant testes and wild-type testes reveals for the first time the existence of single bromodomain BET proteins in animals, as well as evidence for a complex containing tBRDs and tTAFs that regulates transcription of a subset of genes with relevance for spermiogenesis.
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Stage-specific testes proteomics of Drosophila melanogaster identifies essential proteins for male fertility.
Stefanie M. K. Gärtner,Tim Hundertmark,Hendrik Nolte,Ina Theofel,Zeynep Eren-Ghiani,Carolin Tetzner,Timothy B. Duchow,Christina Rathke,Marcus Krüger,Renate Renkawitz-Pohl +9 more
TL;DR: The catalogue of proteins of the different stages of testis development in D. melanogaster will pave the road for future analyses of spermatogenesis, and analysed the stage-specific synthesis and importance for male fertility of a number of uncharacterized proteins.
Journal ArticleDOI
Distinct CoREST complexes act in a cell-type-specific manner
Igor Mačinković,Ina Theofel,Tim Hundertmark,Kristina Kovač,Stephan Awe,Jonathan Lenz,Ignasi Forné,Boris Lamp,Andrea Nist,Axel Imhof,Thorsten Stiewe,Renate Renkawitz-Pohl,Christina Rathke,Alexander Brehm +13 more
TL;DR: This study uncovers three distinct dCoREST complexes that function in a lineage-restricted fashion to repress specific sets of genes thereby maintaining cell-type-specific gene expression programmes.