R
Rainer Renkawitz
Researcher at University of Giessen
Publications - 108
Citations - 9912
Rainer Renkawitz is an academic researcher from University of Giessen. The author has contributed to research in topics: CTCF & Chromatin. The author has an hindex of 50, co-authored 108 publications receiving 9503 citations. Previous affiliations of Rainer Renkawitz include University of Liège & Max Planck Society.
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CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
TL;DR: CTCF is an evolutionarily conserved zinc finger phosphoprotein that binds through combinatorial use of its 11 ZFs to approximately 50 bp target sites that have remarkable sequence variation and emerges as a central player in networks linking expression domains with epigenetics and cell growth regulation.
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Many transcription factors interact synergistically with steroid receptors
TL;DR: A steroid responsive unit can be composed of several modules that, if positioned correctly, act synergistically, according to the degree of synergism of the GRE.
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Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site.
TL;DR: It is shown that the chicken lysozyme silencer S-2.4 kb has many other characteristics in common with enhancer elements, including the fact that the palindromic sequence is inverted.
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The glucocorticoid receptor
Marc Muller,Rainer Renkawitz +1 more
TL;DR: The GR is the receptor to which cortisol and other glucocorticoids bind, and Dexamethasone is an agonist, and RU486 and cyproterone acetate are antagonists of the GR.
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BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma
Dmitri Loukinov,Elena M. Pugacheva,Sergei Vatolin,Svetlana Pack,Hanlim Moon,Igor Chernukhin,Poonam Mannan,Erik G. Larsson,Chandrasekhar Kanduri,Alexander A. Vostrov,Hengmi Cui,Emily L. Niemitz,John E.J. Rasko,Malathi K. Kistler,Joseph J. Breen,Zhengping Zhuang,Wolfgang W. Quitschke,Rainer Renkawitz,Elena Klenova,Andrew P. Feinberg,Rolf Ohlsson,Herbert C. Morse,Victor V. Lobanenkov +22 more
TL;DR: It is shown here that erasure of methylation marks during male germ-line development is associated with dramatic up- regulation of BORIS and down-regulation of CTCF expression, and BORis is a candidate protein for the elusive epigenetic reprogramming factor acting in the male germ line.