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Inga Hansson
Researcher at Uppsala University
Publications - 13
Citations - 642
Inga Hansson is an academic researcher from Uppsala University. The author has contributed to research in topics: Arthritis & Melatonin. The author has an hindex of 12, co-authored 13 publications receiving 612 citations.
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Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.
TL;DR: The results indicate that oxidative and ER induced stress causing caspase-12 activation are involved in neuronal death and disease progression in ALS.
Journal ArticleDOI
The pineal hormone melatonin exaggerates development of collagen-induced arthritis in mice
TL;DR: The hypothesis that the pineal gland can exaggerate the development of CIA via a high release of melatonin, probably via enhancement of T-cell priming is supported.
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XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.
TL;DR: Data support the view that XIAP has beneficial effects in ALS and extends survival and the neuroprotective effect of XIAP involves inhibition of caspases and the stabilization of the calpastatin/calpain system that is altered in the ALS mice.
Journal ArticleDOI
GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background.
Sanna-Maria Hede,Inga Hansson,Gijs B. Afink,Anna Eriksson,Inga Nazarenko,Johanna Andrae,Johanna Andrae,Guillem Genové,Bengt Westermark,Monica Nistér +9 more
TL;DR: An unexpected plasticity of all astrocytic cells in the adult brain, not only of SVZ cells is indicated, and a contribution of widely distributed Pdgfrα+ precursor cells inThe tumorigenic process is indicated.
Journal Article
XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS
TL;DR: In this article, the authors showed that X-linked Inhibitor of Apoptosis Protein (XIAP) has beneficial effects in ALS and extends survival in transgenic mice.