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Laura Korhonen

Researcher at Turku University Hospital

Publications -  119
Citations -  11305

Laura Korhonen is an academic researcher from Turku University Hospital. The author has contributed to research in topics: Programmed cell death & Neural stem cell. The author has an hindex of 43, co-authored 116 publications receiving 10333 citations. Previous affiliations of Laura Korhonen include Helsinki University Central Hospital & Harvard University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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ER stress and neurodegenerative diseases.

Dan Lindholm, +2 more
- 01 Mar 2006 - 
TL;DR: The possible role of ER stress in neurodegenerative diseases is discussed, and current knowledge in this field that may reveal novel insight into disease mechanisms and help to design better therapies for these disorders are highlighted.
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Endoplasmic Reticulum Stress Inhibition Protects against Excitotoxic Neuronal Injury in the Rat Brain

Anna-Leena Sokka, +8 more
- 24 Jan 2007 - 
TL;DR: Salubrinal, inhibiting eIF2α (eukaryotic translation initiation factor 2 subunit α) dephosphorylation, significantly reduced KA-induced ER stress and neuronal death in vivo and in vitro and show that ER responses are essential parts of excitotoxicity mediated by glutamate receptor activation.
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Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

Giuseppa Mudò, +13 more
- 01 Apr 2012 - 
TL;DR: It is shown here that transgenic mice overexpressing PGC-1 α in dopaminergic neurons are resistant against cell degeneration induced by the neurotoxin MPTP, and RSV and other compounds acting via SIRT1/PGC-1α may prove useful as neuroprotective agents in PD and possibly in other neurological disorders.
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Estrogen-receptor-dependent regulation of neural stem cell proliferation and differentiation.

Karin Brännvall, +2 more
- 01 Nov 2002 - 
TL;DR: The data show that estrogen, via ER, affects the proliferation and differentiation of NSC cells, probably acting in conjunction with other factors governing NSC development.