Inge Hamming

TL;DR: ACE2 is abundantly present in humans in the epithelia of the lung and small intestine, which might provide possible routes of entry for the SARS‐CoV.

TL;DR: The renin–angiotensin–aldosterone system (RAAS) is a key regulator of systemic blood pressure and renal function and a key player in renal and cardiovascular disease.

TL;DR: In primary and secondary renal disease, and in transplanted kidneys, neo‐expression of ACE2 occurs in glomerular and peritubular capillary endothelium, with no differences between the various renal disorders, or between acute and chronic rejection and control transplants.

TL;DR: The findings demonstrate that the deleterious effects of AngII on podocytes and its pathogenic role in glomerular disease involve enhanced TRPC6 expression via a calcineurin/NFAT positive feedback signaling pathway.

TL;DR: Urinary KIM-1 level was increased in patients with nondiabetic CKD with proteinuria and decreased in parallel withproteinuria by usingLosartan, sodium restriction, their combination, losartan plus HCT, and the latter plus sodium restriction; consistent with the hypothesis of amelioration of proteinuria-induced tubular damage.