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Isabel dos-Santos-Silva
Researcher at University of London
Publications - 10
Citations - 2399
Isabel dos-Santos-Silva is an academic researcher from University of London. The author has contributed to research in topics: Breast cancer & Population. The author has an hindex of 7, co-authored 10 publications receiving 1674 citations.
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Journal ArticleDOI
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults.
Krishnan Bhaskaran,Ian J. Douglas,Harriet Forbes,Isabel dos-Santos-Silva,David A. Leon,Liam Smeeth +5 more
TL;DR: BMI is associated with cancer risk, with substantial population-level effects, and the heterogeneity in the effects suggests that different mechanisms are associated with different cancer sites and different patient subgroups.
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Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
Krishnan Bhaskaran,Isabel dos-Santos-Silva,David A. Leon,David A. Leon,Ian J. Douglas,Liam Smeeth +5 more
TL;DR: BMI was associated with all cause of death categories except for transport-related accidents, but the shape of the association varied, and the BMI associated with lowest mortality risk was higher in older individuals than in younger individuals.
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Stage at diagnosis of breast cancer in sub-Saharan Africa: a systematic review and meta-analysis
Elima Jedy-Agba,Valerie McCormack,Clement Adebamowo,Clement Adebamowo,Isabel dos-Santos-Silva +4 more
TL;DR: The percentage of patients with late-stage disease at diagnosis in black Africans decreased over time, but it was still higher around 2010 than it was in white and black women in the USA 40 years previously.
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Mammographic density and ageing : A collaborative pooled analysis of cross-sectional data from 22 countries worldwide
Anya Burton,Gertraud Maskarinec,Beatriz Pérez-Gómez,Celine M. Vachon,Hui Miao,Martin Lajous,Ruy Lopez-Ridaura,Megan S. Rice,Ana Pereira,María Luisa Garmendia,Rulla M. Tamimi,Kimberly A. Bertrand,Ava Kwong,Giske Ursin,Giske Ursin,Eunjung Lee,Samera Azeem Qureshi,Huiyan Ma,Sarah Vinnicombe,Sue Moss,Steve Allen,Rose Ndumia,Sudhir Vinayak,Soo Hwang Teo,Shivaani Mariapun,Farhana Fadzli,Beata Peplonska,Agnieszka Bukowska,Chisato Nagata,Jennifer Stone,John L. Hopper,Graham G. Giles,Graham G. Giles,Vahit Ozmen,Mustafa Erkin Aribal,Joachim Schüz,Carla H. van Gils,Johanna O. P. Wanders,Reza Sirous,Reza Sirous,Mehri Sirous,John H. Hipwell,Jisun Kim,Jong Won Lee,Caroline Dickens,Mikael Hartman,Kee Seng Chia,Christopher G. Scott,Anna M. Chiarelli,Linda Linton,Marina Pollán,Anath Arzee Flugelman,Dorria Salem,Rasha Kamal,Norman F. Boyd,Isabel dos-Santos-Silva,Valerie McCormack +56 more
TL;DR: Cross-sectional differences in MD by age and menopausal status in over 11,000 breast-cancer-free women aged 35–85 years are examined, suggesting that younger ages may be the more critical periods for lifestyle modifications aimed at breast density and breast cancer risk reduction.
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Receptor-defined subtypes of breast cancer in indigenous populations in Africa: a systematic review and meta-analysis.
TL;DR: The published data from the more appropriate prospectively measured specimens are consistent with the majority of breast cancers in Africa being ER+.