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Open AccessJournal ArticleDOI

Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults.

TLDR
BMI is associated with cancer risk, with substantial population-level effects, and the heterogeneity in the effects suggests that different mechanisms are associated with different cancer sites and different patient subgroups.
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This article is published in The Lancet.The article was published on 2014-08-30 and is currently open access. It has received 1266 citations till now. The article focuses on the topics: Population.

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Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohammad H. Forouzanfar, +736 more
- 05 Dec 2015 - 
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as discussed by the authors provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: A systematic analysis for the Global Burden of Disease Study 2015

Mohammad H Forouzanfar, +653 more
TL;DR: The comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study 2015 was used to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational risks or clusters of risks from 1990 to 2015.
Journal ArticleDOI

Data Resource Profile: Clinical Practice Research Datalink (CPRD)

TL;DR: The CPRD primary care database is a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies, health-related behaviours and referrals to secondary care, but researchers must be aware of the complexity of routinely collected electronic health records.
Journal ArticleDOI

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013

Mohammad H. Forouzanfar, +721 more
- 05 Dec 2015 - 
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as mentioned in this paper provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.
References
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Journal ArticleDOI

Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies.

Chizuru Nishida
- 10 Jan 2004 - 
TL;DR: The proportion of Asian people with a high risk of type 2 diabetes and cardiovascular disease is substantial at BMIs lower than the existing WHO cut-off point for overweight (> or =25 kg/m2), but available data do not necessarily indicate a clear BMI cut-offs point for all Asians for overweight or obesity.
Journal ArticleDOI

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

TL;DR: Current patterns of overweight and obesity in the United States could account for 14 percent of all deaths from cancer in men and 20 percent of those in women, and increased body weight was associated with increased death rates for all cancers combined and for cancers at multiple specific sites.
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Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

TL;DR: In this article, the authors quantify the effect of physical inactivity on these major non-communicable diseases by estimating how much disease could be averted if inactive people were to become active and to estimate gain in life expectancy at the population level.
Journal ArticleDOI

Proportional hazards tests and diagnostics based on weighted residuals

TL;DR: In this article, Chen et al. showed that a treatment effect that decreases with time can be directly visualized by smoothing an appropriate residual plot, which can be expressed as a weighted least-squares line fitted to the residual plot.

Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

TL;DR: In this article, the authors quantify the effect of physical inactivity on these major non-communicable diseases by estimating how much disease could be averted if inactive people were to become active and to estimate gain in life expectancy at the population level.
Related Papers (5)

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

Marie Ng, +141 more
- 30 Aug 2014 -