Showing papers by "Israel Liberzon published in 2000"
TL;DR: It is suggested that pictorial complexity, as indexed by the authors' semantic measure, does not account for the modulation of visual cortex by aversive, emotional stimuli, and not just aversive stimuli.
161 citations
TL;DR: In this paper, the authors mapped regional brain activity and peripheral psychophysiologic responses, occurring in response to evocative emotional stimuli, and examined whether task instructions could modulate limbic activation.
140 citations
TL;DR: In this article, subjective and psychophysiological emotion responses to standardized visual stimuli in combat veterans with posttraumatic stress disorder (PTSD), combat veterans without PTSD, and nontraumatized controls were examined.
53 citations
TL;DR: A 4-hour pilot workshop to teach psychiatry residents ethnic and cultural issues in patient care and there was statistically significant improvement in performance on questionnaires after the workshop.
Abstract: Efforts have been made to develop a core curriculum for cultural sensitivity training for psychiatry residents. There is a lack of literature reporting effectiveness of various teaching modalities for such training. The authors report their experience with a 4-hour pilot workshop to teach psychiatry residents ethnic and cultural issues in patient care. Pretest and posttest questionnaires were designed to measure residents’ knowledge of cultural issues. There was statistically significant improvement in performance on questionnaires after the workshop (F = 30.6; P<0.001). Further studies are necessary to examine teaching modalities in residency education.
16 citations
1 citations
TL;DR: It is demonstrated that emotional content evokes processing in early sensory cortical regions as well as subcortical, limbic structures aswell as sublenticular/accumbens area.
1 citations
01 Jan 2000
TL;DR: In this paper, the authors proposed a neuropsychological hypothesis for post-traumatic stress disorder, suggesting that neuroanatomical changes as a result of stress and stress-related neuroendocrine changes might underlie symptoms of PTSD.
Abstract: The last decade has witnessed a major transformation in the concepts of mental function and behavior. Dualistic models, such as mental versus physical or psychological versus biological, are giving way to more integrative views of the functional organism, where function and structure are interrelated and affect each other. New concepts of neuroplasticity and improved tools of visualization have both provided a conceptual frame and demonstrated this structure-function interaction. These developments also offer a new conceptualization of psychiatric disorders, which were traditionally seen as psychological or functional in nature. In traditional dualistic terms, post-traumatic stress disorder has been considered a preeminently functional disorder. However, in 1987 Lawrence Kolb (1987) proposed a neuropsychological hypothesis for PTSD, suggesting that neuroanatomical changes as a result of stress and stress-related neuroendocrine changes might underlie symptoms of PTSD. Since then, multiple lines of evidence have demonstrated stress-related neurobiological changes and neuroanatomical sequelae of traumatic exposure. Accordingly, an increasing number of investigators are actively pursuing possible structural or functional neuroanatomical abnormalities that are associated with PTSD or that underlie PTSD symptomatology.