I
Ivo Bendix
Researcher at University of Duisburg-Essen
Publications - 68
Citations - 2212
Ivo Bendix is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Hyperoxia & Neuroprotection. The author has an hindex of 21, co-authored 61 publications receiving 1706 citations. Previous affiliations of Ivo Bendix include Boston Children's Hospital & Charité.
Papers
More filters
Journal ArticleDOI
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
Timour Prozorovski,Ulf Schulze-Topphoff,Robert Glumm,Jan Baumgart,Friederike Schröter,Olaf Ninnemann,Elise Siegert,Ivo Bendix,Oliver Brüstle,Robert Nitsch,Frauke Zipp,Orhan Aktas +11 more
TL;DR: Under oxidative conditions in vitro and in vivo, Sirt1 was upregulated in NPCs, bound to the transcription factor Hes1 and subsequently inhibited pro-neuronal Mash1, and provided evidence for an as yet unknown metabolic master switch that determines the fate of neural progenitors.
Journal ArticleDOI
Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury.
Karla Drommelschmidt,Meray Serdar,Ivo Bendix,Josephine Herz,Frederik Bertling,Sebastian Prager,Matthias Keller,Anna Kristin Ludwig,Vikas Duhan,Stefan Radtke,Kyra de Miroschedji,Peter A. Horn,Yohan van de Looij,Bernd Giebel,Ursula Felderhoff-Müser +14 more
TL;DR: MSC-EVs ameliorate inflammation-induced cellular damage in a rat model of preterm brain injury and may serve as a novel therapeutic option by prevention of neuronal cell death, restoration of white matter microstructure, reduction of gliosis and long-term functional improvement.
Journal ArticleDOI
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Ulf Schulze-Topphoff,Alexandre Prat,Timour Prozorovski,Timour Prozorovski,Volker Siffrin,Magdalena Paterka,Josephine Herz,Ivo Bendix,Igal Ifergan,Ines Schadock,Marcelo A. Mori,Jack van Horssen,Friederike Schröter,Friederike Schröter,Alina Smorodchenko,May H. Han,Michael Bader,Lawrence Steinman,Orhan Aktas,Orhan Aktas,Frauke Zipp +20 more
TL;DR: Results suggest that the kallikrein-kinin system is involved in the regulation of CNS inflammation, limiting encephalitogenic T lymphocyte infiltration into the CNS, and provide evidence that Bdkrb1 could be a new target for the treatment of chronic inflammatory diseases such as multiple sclerosis.
Journal ArticleDOI
Effects of repetitive exposure to pain and morphine treatment on the neonatal rat brain
Lasse Dührsen,Sinno H.P. Simons,Mark Dzietko,Kerstin Genz,Ivo Bendix,Vinzenz Boos,Marco Sifringer,Dick Tibboel,Ursula Felderhoff-Mueser +8 more
TL;DR: Severe inflammatory pain and pain caused by repetitive injections in neonatal rats may cause major changes in the developing brain during the first week of life, and Morphine may only protect the newborn brain against these changes in specific situations.
Journal ArticleDOI
Interaction of Inflammation and Hyperoxia in a Rat Model of Neonatal White Matter Damage
Felix Brehmer,Ivo Bendix,Sebastian Prager,Yohan van de Looij,Yohan van de Looij,Barbara S. Reinboth,Julia Zimmermanns,Gerald W. Schlager,Daniela Brait,Marco Sifringer,Stefanie Endesfelder,Stéphane Sizonenko,Carina Mallard,Christoph Bührer,Ursula Felderhoff-Mueser,Bettina Gerstner +15 more
TL;DR: In this article, the influence of systemic lipopolysaccharide (LPS) application on hyperoxia-induced white matter damage (WMD) in newborn rats was investigated.