J
Jan Baumgart
Researcher at Charité
Publications - 5
Citations - 615
Jan Baumgart is an academic researcher from Charité. The author has contributed to research in topics: Signal transduction & Excitatory postsynaptic potential. The author has an hindex of 4, co-authored 5 publications receiving 563 citations.
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Sirt1 contributes critically to the redox-dependent fate of neural progenitors
Timour Prozorovski,Ulf Schulze-Topphoff,Robert Glumm,Jan Baumgart,Friederike Schröter,Olaf Ninnemann,Elise Siegert,Ivo Bendix,Oliver Brüstle,Robert Nitsch,Frauke Zipp,Orhan Aktas +11 more
TL;DR: Under oxidative conditions in vitro and in vivo, Sirt1 was upregulated in NPCs, bound to the transcription factor Hes1 and subsequently inhibited pro-neuronal Mash1, and provided evidence for an as yet unknown metabolic master switch that determines the fate of neural progenitors.
Journal ArticleDOI
Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling
Thorsten Trimbuch,Prateep Beed,Johannes Vogt,Sebastian Schuchmann,Nikolaus Maier,Michael Kintscher,Jörg Breustedt,Markus Schuelke,Nora Streu,Olga Kieselmann,Irene Brunk,Gregor Laube,Ulf Strauss,Arne Battefeld,Hagen Wende,Carmen Birchmeier,Stefan Wiese,Michael Sendtner,Hiroshi Kawabe,Mika Kishimoto-Suga,Nils Brose,Jan Baumgart,Beate Geist,Junken Aoki,Nic E. Savaskan,Anja U. Bräuer,Jerold Chun,Olaf Ninnemann,Dietmar Schmitz,Robert Nitsch +29 more
TL;DR: PRG-1 is proposed as an important player in the modulatory control of hippocampal excitability dependent on presynaptic LPA(2) receptor signaling.
Journal ArticleDOI
The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity
Nicola Brandt,Kristin Franke,Mladen-Roko Rasin,Jan Baumgart,Johannes Vogt,Sergey Khrulev,Burkhard Hassel,Elena E. Pohl,Nenad Sestan,Robert Nitsch,Stefan Schumacher +10 more
TL;DR: Findings reveal a novel switch of specificity in signaling leading to neuronal process differentiation in consecutive developmental events in patients with mental retardation.
Journal ArticleDOI
Model of wound healing for esophagogastric anastomoses in rats.
TL;DR: The rat model for performing esophagogastric anastomoses after gastric tube formation may serve as a functional and useful model in future research studies on microvascular and molecular processes of anastmotic healing.
Journal ArticleDOI
Contents Vol. 48, 2012
Stefan A. Maier,T. Schäfer,J. Sperling,JE Slotta,Otto Kollmar,Martin K. Schilling,Michael D. Menger,Sven Richter,H. Anetzberger,A. Mayer,Christoph Schulz,Magdalena Müller-Gerbl,Stephanie Denk,M. Perl,M. Huber-Lang,P. Menges,Wolfram Kessler,C. Kloecker,M. Feuerherd,S. Gaubert,S. Diedrich,J. van der Linde,A. Hegenbart,Alexandra Busemann,Tobias Traeger,K. Cziupka,Claus-Dieter Heidecke,Max Ditzel,Eva B. Deerenberg,Niels Komen,Irene M. Mulder,Hans Jeekel,Janusz Lange,P. Djoric,J. Zeleskov-Djoric,D.M. Stanisavljevic,Z.D. Markovic,Vladimir Zivkovic,Milena Vuletic,Dragan M. Djuric,Vladimir Jakovljevic,Daniel Drescher,Johannes Vogt,M Gabriel,Jan Baumgart,C.C. Schimanski,Hauke Lang,I. Gockel,Satz Mengensatzproduktion,Druck Reinhardt Druck Basel +49 more
TL;DR: In this article, the authors present an overview of the state-of-the-art clinical and experimental data from the Akita Clinical and Experimental Surgery (ACES) program.