J
J. Carlos Menéndez
Researcher at Complutense University of Madrid
Publications - 336
Citations - 7983
J. Carlos Menéndez is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Catalysis & Michael reaction. The author has an hindex of 37, co-authored 317 publications receiving 6784 citations. Previous affiliations of J. Carlos Menéndez include Université Paul Cézanne Aix-Marseille III & Universiti Sains Malaysia.
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Synthesis of a library of 5,6-unsubstituted 1,4-dihydropyridines based on a one-pot 4CR/elimination process and their application to the generation of structurally diverse fused nitrogen heterocycles.
TL;DR: The application of 1,4-dihydropyridines to the facile generation of molecular diversity and complexity was demonstrated by employing them as dienophiles for Yb(OTf)(3)-catalyzed imino Diels-Alder (Povarov) reactions leading diastereoselectively to hexahydrobenzo[h]naphthyridine derivatives containing three adjacent stereocenters.
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New Synthetic Applications of Aryllead Triacetates. N-Arylation of Amides
TL;DR: Tolyl-lead triacetate efficiently arylates the nitrogen atom of carboxamide, sulfonamide, imide, and hydantoin anions under mild conditions as mentioned in this paper.
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Synthesis of 5,6-Dihydrodibenzo[b,h][1,6]naphthyridines via Copper Bromide Catalyzed Intramolecular [4 + 2] Hetero-Diels-Alder Reactions.
Isravel Muthukrishnan,Perumal Vinoth,Thavaraj Vivekanand,Subbiah Nagarajan,C. Uma Maheswari,J. Carlos Menéndez,Vellaisamy Sridharan +6 more
TL;DR: A highly efficient synthesis of 5,6-dihydrodibenzo[b,h][1,6]naphthyridines was achieved by reaction between 2-(N-propargylamino)benzaldehydes and arylamines in the presence of CuBr2.
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New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.
Giammarco Tenti,Esther Parada,Rafael León,Javier Egea,Sonia Martínez-Revelles,Ana M. Briones,Vellaisamy Sridharan,Manuela G. López,María Teresa Ramos,J. Carlos Menéndez +9 more
TL;DR: C5-unsubstituted-C6-aryl-1,4-dihydropyridines were prepared by a CAN-catalyzed multicomponent reaction from chalcones, β-dicarbonyl compounds, and ammonium acetate and were able to protect neuroblastoma cells against Ca(2+) overload and oxidative stress models.
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Efficient generation of highly functionalized fused oxazepine frameworks based on a CAN-catalyzed four-component tetrahydropyridine synthesis/ring-closing metathesis sequence.
TL;DR: 1-Allyl(propargyl)-6-allyl(Propargyl)oxy-1,4,5,6-tetrahydropyridines, obtained through a CAN-catalyzed four-component reaction, were transformed into highly functionalized pyrido[2,1-b][1,3]oxazepines by ring-closing metathesis (RCM) and RCEYM processes, which constitute the first examples of