J
J. Carlos Menéndez
Researcher at Complutense University of Madrid
Publications - 336
Citations - 7983
J. Carlos Menéndez is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Catalysis & Michael reaction. The author has an hindex of 37, co-authored 317 publications receiving 6784 citations. Previous affiliations of J. Carlos Menéndez include Université Paul Cézanne Aix-Marseille III & Universiti Sains Malaysia.
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Book ChapterDOI
Stereoselective organic synthesis in water: Organocatalysis by proline and its derivatives
B.S. Vachan,Muthu Karuppasamy,Perumal Vinoth,Vellaisamy Sridharan,Vellaisamy Sridharan,J. Carlos Menéndez +5 more
TL;DR: In this paper, the main developments on stereoselective reactions performed in water and using proline or proline derivatives as catalysts are summarized in detail and reactions catalyzed by solid-supported proline derivative are also discussed in detail.
Journal ArticleDOI
CAN-Catalyzed Three-Component Reaction Between Anilines and Alkyl Vinyl Ethers: Stereoselective Synthesis of 2-Methyl-1,2,3,4-tetrahydroquinolines and Studies on Their Aromatization.
TL;DR: The CAN-catalyzed reaction between anilines and vinyl ethers at room temperature provides a convenient and efficient access to 4-alkoxy-2-methyl-1,2,3,4-tetrahydroquinolines.
Book ChapterDOI
Antimetabolites That Interfere with Nucleic Acid Biosynthesis
TL;DR: The catalysis of thymidylate synthase (TS), a reductive methylation that involves the transfer of a carbon atom from the cofactor 5,10-methylenetetrahydrofolate to the 5 position of the pyrimidine ring, is analyzed in detail as well as the compounds that modulate its activity.
Journal ArticleDOI
CAN-Catalyzed Vinylogous Povarov Reactions: The First Three-Component Synthesis of 2-Functionalized Tetrahydroquinolines from Anilines, -Cinnamaldehyde and Vinyl Ethers
TL;DR: The CAN-catalyzed reaction between anilines, cinnamaldehyde and vinyl ethers affords 2-styryl-1,2,3,4-tetrahydroquinolines as discussed by the authors.
Journal ArticleDOI
Three-component synthesis of highly functionalized aziridines containing a peptide side chain and their one-step transformation into β-functionalized α-ketoamides.
TL;DR: This method allows the preparation of N-unprotected, trisubstituted aziridines bearing a peptide side chain under mild conditions and transformation into β-trifluoroacetamido-α-ketoamide and α,β-diketoamide frameworks was achieved in a single step.