J
Jacob G. Bundy
Researcher at Imperial College London
Publications - 99
Citations - 7743
Jacob G. Bundy is an academic researcher from Imperial College London. The author has contributed to research in topics: Metabolomics & Metabolite. The author has an hindex of 42, co-authored 95 publications receiving 6897 citations. Previous affiliations of Jacob G. Bundy include Macaulay Institute & King's College London.
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Fluorodeoxyuridine affects the identification of metabolic responses to daf-2 status in Caenorhabditis elegans
TL;DR: The effects of FUdR were much greater than the effects of the mutation, and there were clear interactions between F UdR and genotype, such that identification of daf-2-dependent metabolites would have been compromised on FUDR plates.
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Investigation of the physiological relationship between the cyanide-insensitive oxidase and cyanide production in Pseudomonas aeruginosa.
James E. A. Zlosnik,Gholam Reza Tavankar,Jacob G. Bundy,Dimitris Mossialos,Ronan F. O’Toole,Huw D. Williams +5 more
TL;DR: It was found that cyanide is produced in P. aeruginosa at similar levels irrespective of its complement of CIO, indicating that the CIO is not an obligatory electron sink for cyanide synthesis, and may in part rely upon fermentation for energy generation in stationary phase.
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Influence of the Crc regulator on the hierarchical use of carbon sources from a complete medium in Pseudomonas
Ruggero La Rosa,Volker Behrends,Volker Behrends,Huw D. Williams,Jacob G. Bundy,Fernando Rojo +5 more
TL;DR: Unexpectedly, the loss of Crc led both species to excrete acetate and pyruvate as a result of unbalanced growth during exponential phase, compounds that were later consumed in stationary phase, which helps to explain the contribution of the Crc/Hfq regulatory system to evolutionary fitness of pseudomonads.
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Application of bioluminescence‐based microbial biosensors to the ecotoxicity assessment of organotins
TL;DR: The toxicity of two common organotin pollutants and their initial breakdown products were assessed using two different bioluminescent microbial biosensors: Microtox and lux‐modified Pseudomonas fluorescens pUCD 607.
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Metallothioneins may not be enough--the role of phytochelatins in invertebrate metal detoxification.
TL;DR: There is growing evidence that phytochelatins may be important in many different animal species, and may play a holding role, mopping up free metal ions until the (relatively slow) induction and synthesis of metallothionein proteins.