J
Jacob G. Bundy
Researcher at Imperial College London
Publications - 99
Citations - 7743
Jacob G. Bundy is an academic researcher from Imperial College London. The author has contributed to research in topics: Metabolomics & Metabolite. The author has an hindex of 42, co-authored 95 publications receiving 6897 citations. Previous affiliations of Jacob G. Bundy include Macaulay Institute & King's College London.
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Journal ArticleDOI
Standard reporting requirements for biological samples in metabolomics experiments: environmental context
Norman Morrison,Dan Bearden,Jacob G. Bundy,Tim Collette,Felicity Currie,Matthew P. Davey,Nathan S. Haigh,David Hancock,Oliver A.H. Jones,Simone Rochfort,Susanna-Assunta Sansone,Dalibor Štys,Dalibor Štys,Quincy Teng,Dawn Field,Mark R. Viant +15 more
TL;DR: These reporting requirements should guide and support the standardised annotation, dissemination and interpretation of environmental metabolomics meta-data.
Journal ArticleDOI
An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress.
TL;DR: The endogenous metabolites of the coelomic fluid of the earthworm Eisenia veneta were characterised using high‐resolution one‐dimensional and two‐dimensional 1H nuclear magnetic resonance spectroscopy and identified together with adenosine and nicotinamide mononucleotide.
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NMR-derived developmental metabolic trajectories: an approach for visualizing the toxic actions of trichloroethylene during embryogenesis
Mark R. Viant,Jacob G. Bundy,Christopher A. Pincetich,Jeffrey S. De Ropp,Ronald S. Tjeerdema +4 more
TL;DR: The results support the continued development of NMR-based metabolomics as a rapid and reproducible tool for biomarker discovery and environmental risk assessment.
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Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis.
Wynne D. Smith,Emmanuelle Bardin,Loren Cameron,Claire Edmondson,Katie V. Farrant,Isaac Martin,R.A. Murphy,Odel Soren,A. Turnbull,Natasha Wierre-Gore,Eric W.F.W. Alton,Jacob G. Bundy,Andrew Bush,Gary Connett,Saul N. Faust,Alain Filloux,Paul S. Freemont,Andrew L. Jones,Zoltan Takats,Jeremy S. Webb,Huw D. Williams,Jane C. Davies +21 more
TL;DR: New treatments that target the primary defect in cystic fibrosis, recently licensed for use, have been associated with a fall in P. aeruginosa infection prevalence, which could enable more successful eradication before chronic infection is established.
Journal ArticleDOI
Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling
Jacob G. Bundy,David J. Spurgeon,Claus Svendsen,Peter K. Hankard,Daniel Osborn,John C. Lindon,Jeremy K. Nicholson +6 more
TL;DR: The results show that two morphologically undistinguishable species (E. fetida and E. andrei) differ markedly in their biochemical profiles despite apparently occupying the same ecological niche, and indicate that metabolic phenotype profiling can be used as a powerful functional genomics tool.