J
James Alexis Platts
Researcher at Cardiff University
Publications - 241
Citations - 7776
James Alexis Platts is an academic researcher from Cardiff University. The author has contributed to research in topics: Hydrogen bond & Density functional theory. The author has an hindex of 42, co-authored 231 publications receiving 7152 citations. Previous affiliations of James Alexis Platts include University of South Australia & Aarhus University.
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A Multi-Level Theoretical Study to Disclose the Binding Mechanisms of Gold(III)-Bipyridyl Compounds as Selective Aquaglyceroporin Inhibitors.
Valentina Graziani,Alessandro Marrone,Nazzareno Re,Cecilia Coletti,James Alexis Platts,Angela Casini +5 more
TL;DR: The overall importance of three key aspects for AQP3 inhibition are spotlights: water speciation of the AuIII complex, stability of non-covalent adducts and conformational changes induced within the pore by the coordinative binding of AuIII.
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The Lennard-Jones Function: A Quantitative Description of the Spatial Correlation of Electrons As Determined by the Exclusion Principle
TL;DR: In this paper, the conditional probability for same-spin electrons (CPNE) was used as the basis for the VSEPR model, which is called the Lennard-Jones function (LJF).
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A Theoretical Study of the Proton-Bound Ammonia Dimer
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Small-molecule G-quadruplex interactions: Systematic exploration of conformational space using multiple molecular dynamics
TL;DR: An approach to overcome the challenge of quadruplex conformational flexibility is presented here, which uses a combined multiple molecular dynamics and sampling approach and two test small molecules have been used, RHPS4 and pyridostatin, which themselves have contrasting degrees of conformational flexible.
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Experimental charge density analysis of a gallium(I) N-heterocyclic carbene analogue.
TL;DR: The utility of experimental charge density analysis as a technique to investigate the unusual bonding and electronic characteristics of low oxidation state/low coordinate p-block complexes is highlighted.