J
James Alexis Platts
Researcher at Cardiff University
Publications - 241
Citations - 7776
James Alexis Platts is an academic researcher from Cardiff University. The author has contributed to research in topics: Hydrogen bond & Density functional theory. The author has an hindex of 42, co-authored 231 publications receiving 7152 citations. Previous affiliations of James Alexis Platts include University of South Australia & Aarhus University.
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Prediction of fluorophilicity of organic and transition metal compounds using molecular surface areas
TL;DR: In this paper, a model for the prediction of fluorophilicity based on the regression of experimental values for 93 organic molecules against molecular surface area descriptors has been constructed, which is predictively accurate, with R 2 = 0.94 and RMS=0.638.
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Exploring the cellular uptake and localisation of phosphorescent rhenium fac-tricarbonyl metallosurfactants as a function of lipophilicity
Andrew Jon Hallett,Emeline Placet,Roxane Prieux,Danielle McCafferty,James Alexis Platts,David Lloyd,Marc D. Isaacs,Anthony Joseph Hayes,Simon J. Coles,Mateusz B. Pitak,Sarah Marchant,Stephen N. Marriott,Rudolf Konrad Allemann,Athanasia Dervisi,Ian Andrew Fallis +14 more
TL;DR: Interestingly, complexes of intermediate lipophilicity such as 7+ and 8+ showed reasonable uptake, proved to be non-toxic, and were capable of crossing exterior cell walls and localising in the organelles of the cells.
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Platinum trimethyl bipyridyl thiolates--new, tunable, red- to near IR emitting luminophores for bioimaging applications.
TL;DR: Synthetic, spectroscopic, computational and biological imaging studies of platinum trimethyl bipyridyl thiolate complexes of the general formula reveal these to be easily accessed, tunable bioimaging agents which feature an unusual σ-π* Inter-Ligand Charge Transfer (ILCT) transition.
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Wood Protection Properties of Quaternary Ammonium Arylspiroborate Esters Derived from Naphthalene 2,3-Diol, 2,2′-Biphenol and 3-Hydroxy-2-naphthoic Acid
Jenny M. Carr,Peter J. Duggan,David Humphrey,James Alexis Platts,Edward M. Tyndall,Edward M. Tyndall +5 more
TL;DR: In this paper, three lipophilic tetra-n-butylammonium spiroborates, including 2,2′-biphenol 5 and 3, were developed and tested.
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Computational evidence for structural consequences of kiteplatin damage on DNA
TL;DR: Insight is revealed into how kiteplatin binds to DNA and similarities and differences between this and related compounds, thus revealing insights into how cisplatin and oxaliplatin bind to DNA.