James C. McRea

TL;DR: ReGel's inherent ability to solubilize (400 to >2000-fold) and stabilize poorly soluble and sensitive drugs, including proteins is a substantial benefit and the gel provided excellent control of the release of paclitaxel for approximately 50 days.

TL;DR: In this article, a combination device for salvaging blood comprises a closed plasma chamber containing a plasma chamber solution, a hollow fiber plasma-separating membrane for receiving blood and permitting plasma to be transported therethrough into the plasma chamber solutions and for refiltering the treated plasma back into the blood circuit, and an ultrafiltration membrane for removing water, fluids, and low molecular weight components from the plasma.

TL;DR: In this paper, a system and method of achieving both convective and diffusive transport of plasma across a membrane accompanied by the selective removal of plasma components using sorbents followed by reinfusion of the purified plasma in a blood circulation system is achieved by pumping blood through a filter comprising a bundle of "U" shaped hollow fibers immersed in a closed plasma chamber.

TL;DR: Immobilized heparin-polyurethane catheters implanted in canine femoral and jugular veins for 1 h periods exhibited significant reduction in thrombus formation compared with untreated PU contralateral controls and provided even greater improvement in antithrombogenicity.

TL;DR: In vitro characterization of the complementary and competitive binding behavior of the Con A-G-insulin complexes has shown that, when challenged with varying concentrations of glucose, corresponding levels of G- Insulin are released and it has been shown that G-ins insulin exhibits enhanced stability against aggregation.