Z
Zina Moldoveanu
Researcher at University of Alabama at Birmingham
Publications - 178
Citations - 11731
Zina Moldoveanu is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Antibody & Immune system. The author has an hindex of 55, co-authored 176 publications receiving 10823 citations. Previous affiliations of Zina Moldoveanu include Nihon University & Osaka University.
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Journal ArticleDOI
Biodegradable block copolymers for delivery of proteins and water-insoluble drugs
Gaylen M. Zentner,Ramesh Rathi,Chung Shih,James C. McRea,Min Hyo Seo,Hunseung Oh,B. G. Rhee,Jiri Mestecky,Zina Moldoveanu,Michael H. Morgan,Steven D. Weitman +10 more
TL;DR: ReGel's inherent ability to solubilize (400 to >2000-fold) and stabilize poorly soluble and sensitive drugs, including proteins is a substantial benefit and the gel provided excellent control of the release of paclitaxel for approximately 50 days.
Journal ArticleDOI
The Pathophysiology of IgA Nephropathy
Hitoshi Suzuki,Krzysztof Kiryluk,Jan Novak,Zina Moldoveanu,Andrew B. Herr,Matthew B. Renfrow,Robert J. Wyatt,Francesco Scolari,Jiri Mestecky,Ali G. Gharavi,Bruce A. Julian +10 more
TL;DR: Recent advances in understanding the biochemical, immunologic, and genetic pathogenesis of IgA nephropathy are discussed, and five distinct susceptibility loci are identified that potentially influence these processes and contain candidate mediators of disease.
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Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity
Hitoshi Suzuki,Run Fan,Zhixin Zhang,Rhubell Brown,Stacy Hall,Bruce A. Julian,W. Winn Chatham,Yusuke Suzuki,Robert J. Wyatt,Zina Moldoveanu,Jeannette Y. Lee,James E. Robinson,Milan Tomana,Yasuhiko Tomino,Jiri Mestecky,Jan Novak +15 more
TL;DR: Findings indicate that glycan-specific antibodies are associated with the development of IgAN and may represent a disease-specific marker and potential therapeutic target.
Journal ArticleDOI
CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus.
Zina Moldoveanu,Laurie Love-Homan,Laurie Love-Homan,Wen Qiang Huang,Wen Qiang Huang,Arthur M. Krieg,Arthur M. Krieg +6 more
TL;DR: St stimulatory CpG ODN are promising new immune enhancers for vaccination applications, suggesting possible utility as vaccine enhancers.
Journal Article
Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding.
TL;DR: It is concluded that KLH feeding induced systemic T cell tolerance, but B cell priming, at both systemic and mucosal sites, and these studies support the concept of using Ag feeding as a treatment for certain immune-mediated diseases.