James Coulter

TL;DR: Under highly controlled conditions, long-term high copper intake results in increases in some indexes of copper status, alters an index of oxidant stress, and affects several indexes of immune function.

TL;DR: It is concluded that a high proportion of healthy elderly people may have suboptimal status for these nutrients despite apparently adequate dietary intakes and riboflavin supplementation at physiologic doses corrects biochemical abnormalities of not only EGRAC, but also plasma PLP, confirming the biochemical interdependency of these vitamins and suggesting that rib oflavin is the limiting nutrient.

TL;DR: Results indicate that serum diamine oxidase activity is sensitive to changes in dietary Cu intakes and may also have the potential to evaluate changes in Cu status in healthy adult human subjects.

TL;DR: Although the disease process per se may explain the lower plasma T3 concentrations, it is also possible, inasmuch as these patients were in early-stage breast cancer, that selenium status may be influencing T3 levels via changes in the activity of the selenoenzyme type 1 iodothyronine deiodinase.

TL;DR: Findings indicated no adverse effects of Zn supplementation on immune status or Cu status and support the US upper level ofZn tolerance of 40 mg/d and could have implications for seasonal variability in the incidence of infectious diseases.