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Open AccessJournal ArticleDOI

Riboflavin and vitamin B-6 intakes and status and biochemical response to riboflavin supplementation in free-living elderly people.

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TLDR
It is concluded that a high proportion of healthy elderly people may have suboptimal status for these nutrients despite apparently adequate dietary intakes and riboflavin supplementation at physiologic doses corrects biochemical abnormalities of not only EGRAC, but also plasma PLP, confirming the biochemical interdependency of these vitamins and suggesting that rib oflavin is the limiting nutrient.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 1998-08-01 and is currently open access. It has received 74 citations till now. The article focuses on the topics: Riboflavin & B vitamins.

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Journal ArticleDOI

Riboflavin (vitamin B-2) and health

TL;DR: There is reasonably good evidence that poor riboflavin status interferes with iron handling and contributes to the etiology of anemia when iron intakes are low, and discrepancies between dietary intake data and biochemical data suggest either that requirements are higher than hitherto thought or that biochemical thresholds for deficiency are inappropriate.
Journal ArticleDOI

Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements.

TL;DR: Exercise appears to decrease nutrient status even further in active individuals with preexisting marginal vitamin intakes or marginal body stores, and active individuals who restrict their energy intake or make poor dietary choices are at greatest risk for poor thiamine, riboflavin, and vitamin B-6 status.
Journal ArticleDOI

Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements

TL;DR: The high tHcy concentration typically associated with homozygosity for the 677C-->T variant of MTHFR occurs only with poor riboflavin status, which may have important implications for governments considering new fortification policies aimed at the prevention of diseases for which this genotype is associated with increased risk.
Journal ArticleDOI

Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease

TL;DR: Oral folic acid plus vitamin B-12 decreased homocysteine concentrations in elderly patients with vascular disease but was not associated with statistically significant beneficial effects on cognitive function over the short or medium term.
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