J
James J. McGough
Researcher at Semel Institute for Neuroscience and Human Behavior
Publications - 161
Citations - 19598
James J. McGough is an academic researcher from Semel Institute for Neuroscience and Human Behavior. The author has contributed to research in topics: Attention deficit hyperactivity disorder & Methylphenidate. The author has an hindex of 71, co-authored 157 publications receiving 17727 citations. Previous affiliations of James J. McGough include University of California, Irvine & University of Notre Dame.
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Journal ArticleDOI
A genomewide scan for attention-deficit/hyperactivity disorder in an extended sample: suggestive linkage on 17p11.
Matthew N. Ogdie,I. Laurence MacPhie,Sonia L. Minassian,May Yang,Simon E. Fisher,Clyde Francks,Rita M. Cantor,James T. McCracken,James J. McGough,Stanley F. Nelson,Anthony P. Monaco,Susan L. Smalley +11 more
TL;DR: Two regions are suggested as highly likely to harbor risk genes for ADHD: 16p13 and 17p11, Interestingly, both regions, as well as 5p13, have been highlighted in genomewide scans for autism.
Journal ArticleDOI
Safety and tolerability of methylphenidate in preschool children with ADHD.
Timothy Wigal,Laurence L. Greenhill,Shirley Chuang,James J. McGough,Benedetto Vitiello,Anne Skrobala,James M. Swanson,Sharon B. Wigal,Howard Abikoff,Scott H. Kollins,James T. McCracken,Mark A. Riddle,Kelly Posner,Jaswinder K. Ghuman,Mark Davies,Ben Thorp,Annamarie Stehli +16 more
TL;DR: Methylphenidate 3- to 5-year-old children with attention-deficit/hyperactivity disorder (ADHD) during 1 year of treatment with methylphenidate (MPH) suffered from emotional outbursts, difficulty falling asleep, repetitive behaviors/thoughts, appetite decrease, and irritability, while parents spontaneously reported moderate to severe AEs.
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Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder.
Susan L. Smalley,Julia N. Bailey,Christina G.S. Palmer,Dennis P. Cantwell,James J. McGough,Melissa Del’Homme,Joan Rosenbaum Asarnow,J. A. Woodward,C. Ramsey,Stan F. Nelson +9 more
TL;DR: Linkage investigations of the VNTR and ADHD in affected sibling pair (ASP) families and singleton families using both the transmission disequilibrium test (TDT) and a mean test of identity-by-descent (IBD) sharing are described.
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Efficacy and tolerability of lisdexamfetamine dimesylate (NRP-104) in children with attention-deficit/hyperactivity disorder: a phase III, multicenter, randomized, double-blind, forced-dose, parallel-group study.
TL;DR: Treatment once daily with the prodrug LDX at doses of 30 to 70 mg appeared to be effective and had a tolerability profile similar to those of currently marketed extended-release stimulants.
Journal ArticleDOI
Stimulant-Related Reductions of Growth Rates in the PATS
James M. Swanson,Laurence L. Greenhill,Timothy Wigal,Scott H. Kollins,Annamarie Stehli,Mark Davies,Shirley Chuang,Benedetto Vitiello,Anne Skrobala,Kelly Posner,Howard Abikoff,Melvin D. Oatis,James T. McCracken,James J. McGough,Mark A. Riddle,Jaswinder K. Ghuman,Charles E. Cunningham,Sharon B. Wigal +17 more
TL;DR: Risks of reduced growth rates should be balanced against expected benefits when preschool-age children are treated with stimulant medication.