James M. Musser

TL;DR: Inactivation of CcpA and CovR alone and in combination led to significant alterations in the transcript levels of several key GAS virulence factor encoding genes during infection, providing new knowledge regarding the molecular mechanisms by which pathogenic bacteria respond to environmental signals to regulate virulence Factors and basic metabolic processes during infection.

TL;DR: In this article, the genetic heterogeneity of 63 community pediatric pharyngeal group A streptococcal (GAS) isolates circulating within a 3-week period were compared with 17 contemporaneous invasive pediatric isolates.

TL;DR: These analyses show that there are notable differences in the genomes of bovine mastitis-associated and human clones of S. aureus and provide a framework for the identification of specific factors associated with host specificity in this major human and animal pathogen.

TL;DR: In this paper, the authors sequenced the genomes of 16,965 SARS-CoV-2 from samples acquired March 15, 2021 through September 20, 2021 in the Houston Methodist hospital system.

TL;DR: Molecular analysis of organisms cultured from seven patients with infections caused by mono-rifampin-resistant M. tuberculosis and 13 additional patients in New York City confirmed independent strain origin, suggesting that host factors such as poor compliance with antituberculosis medications or decreased absorption of rifampsin have been a driving force in the origin of these strains.