J
James M. Musser
Researcher at Houston Methodist Hospital
Publications - 477
Citations - 44674
James M. Musser is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Streptococcus pyogenes & Virulence. The author has an hindex of 113, co-authored 461 publications receiving 42030 citations. Previous affiliations of James M. Musser include Rocky Mountain Laboratories & Baylor College of Medicine.
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Journal ArticleDOI
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences.
Waleed Nasser,Stephen B. Beres,Randall J. Olsen,Melissa A. Dean,Kelsey A. Rice,S. Wesley Long,Karl G. Kristinsson,Magnus Gottfredsson,Jaana Vuopio,Kati Räisänen,Dominique A. Caugant,Martin Steinbakk,Donald E. Low,Allison McGeer,Jessica Darenberg,Birgitta Henriques-Normark,Birgitta Henriques-Normark,Chris A. Van Beneden,Steen Hoffmann,James M. Musser +19 more
TL;DR: Analysis of 3,615 genome sequences permitted us to delineate the nature and timing of molecular events that contributed to an ongoing global human epidemic of infections caused by group A Streptococcus, the “flesh-eating” pathogen, and resolve a decades-long controversy about the type and sequence of genomic alterations that produced this explosive epidemic.
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Genetic diversity and relationships in populations of Bordetella spp.
TL;DR: Bordetella pertussis 18-323, which is used in mouse potency tests of vaccines, is more similar genetically to isolates of B. bronchiseptica and B. parapertussis than to other isolates currently assigned to the species B. pertussi.
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Evolutionary genetic relationships of clones of Salmonella serovars that cause human typhoid and other enteric fevers.
R. K. Selander,P Beltran,N H Smith,R. Helmuth,F. A. Rubin,D. J. Kopecko,K. Ferris,Ben D. Tall,A. Cravioto,James M. Musser +9 more
TL;DR: In this paper, a multilocus enzyme electrophoresis was employed to measure chromosomal genotypic diversity and evolutionary relationships among 761 isolates of the serovars Salmonella typhi, S. sendai and S. paratyphi B, respectively, but cause gastroenteritis in both humans and animals.
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Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Convalescent Plasma.
Eric Salazar,Katherine K. Perez,Madiha Ashraf,Jian Chen,Brian Castillo,Paul A. Christensen,Taryn A Eubank,David W. Bernard,Todd N. Eagar,S. Wesley Long,Sishir Subedi,Randall J. Olsen,Christopher Leveque,Mary R. Schwartz,Monisha Dey,Cheryl Chavez-East,John Rogers,Ahmed Shehabeldin,David Joseph,Guy Williams,Karen D. Thomas,Faisal Masud,Christina Talley,Katharine G. Dlouhy,Bevin Valdez Lopez,Curt Hampton,Jason J. Lavinder,Jimmy Gollihar,Andre C. Maranhao,Gregory C. Ippolito,Matthew Ojeda Saavedra,Concepcion C. Cantu,Prasanti Yerramilli,Layne Pruitt,James M. Musser,James M. Musser +35 more
TL;DR: Administration of convalescent plasma is a safe treatment option for those with severe COVID-19 disease, and whole genome sequencing data did not identify a strain genotype-disease severity correlation.
Journal ArticleDOI
Global genetic structure and molecular epidemiology of encapsulated Haemophilus influenzae.
James M. Musser,J. Simon Kroll,Dan M. Granoff,E. Richard Moxon,Bernard R. Brodeur,José Campos,Henri Dabernat,Wilhelm Frederiksen,Josee Hamel,Gregory Hammond,E. Arne Høiby,Kristin E. Jonsdottir,Mustafa Kabeer,Ingegerd Kallings,Waheed N. Khan,Mogens Kilian,Kathleen Knowles,Hendrik J. Koornhof,Barbara Law,Karl I. Li,Janet Montgomery,Patricia E. Pattison,Jean Claude Piffaretti,Aino K. Takala,Mee Len Thong,Robert Wall,Joel I. Ward,Robert K. Selander +27 more
TL;DR: The analysis suggests that the present distribution of clones is, in part, related to patterns of racial or ethnic differentiation and historical demographic movements of the human host populations.