J
Jan-Eric Turner
Researcher at University of Hamburg
Publications - 55
Citations - 3413
Jan-Eric Turner is an academic researcher from University of Hamburg. The author has contributed to research in topics: Immune system & Glomerulonephritis. The author has an hindex of 28, co-authored 49 publications receiving 2802 citations. Previous affiliations of Jan-Eric Turner include National Institute for Medical Research.
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Journal ArticleDOI
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.
Keiji Hirota,Jan-Eric Turner,Matteo Villa,João H. Duarte,Jocelyne Demengeot,Oliver M. Steinmetz,Brigitta Stockinger +6 more
TL;DR: It is found that endogenous cells of the TH17 subset of helper T cells in lymphoid organs of naive mice 'preferentially' homed to the intestines and were maintained independently of IL-23.
Journal ArticleDOI
IL-9–mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation
Jan-Eric Turner,Peter J. Morrison,Christoph Wilhelm,Christoph Wilhelm,Mark S. Wilson,Helena Ahlfors,Jean-Christophe Renauld,Ulf Panzer,Helena Helmby,Brigitta Stockinger +9 more
TL;DR: IL-9 acts as an autocrine amplifier of type 2 innate lymphoid cell function to promote tissue repair in the recovery phase of helminth-induced lung infection.
Journal ArticleDOI
The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis
Hans-Joachim Paust,Jan-Eric Turner,Oliver M. Steinmetz,Anett Peters,Felix Heymann,Christoph Hölscher,Gunter Wolf,Christian Kurts,Hans-Willi Mittrücker,Rolf A.K. Stahl,Ulf Panzer +10 more
TL;DR: Targeting the IL-23/IL-17 axis may be a promising therapeutic strategy for the treatment of proliferative and crescentic glomerulonephritis.
Journal ArticleDOI
CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis
Jan-Eric Turner,Hans-Joachim Paust,Oliver M. Steinmetz,Anett Peters,Jan-Hendrik Riedel,Annette Erhardt,Claudia Wegscheid,Joachim Velden,Susanne Fehr,Hans-Willi Mittrücker,Gisa Tiegs,Rolf A.K. Stahl,Ulf Panzer +12 more
TL;DR: Data suggest that CCR6 mediates renal recruitment of both T Regs and Th17 cells and that the reduction of anti-inflammatory Tregs in the presence of a fully functional Th1 response aggravates experimental glomerulonephritis.
Journal ArticleDOI
CXCR3 Mediates Renal Th1 and Th17 Immune Response in Murine Lupus Nephritis
Oliver M. Steinmetz,Jan-Eric Turner,Hans-Joachim Paust,Matthias Lindner,Anett Peters,Kirstin Heiss,Joachim Velden,Helmut Hopfer,Susanne Fehr,Thorsten Krieger,Catherine Meyer-Schwesinger,Tobias N. Meyer,Udo Helmchen,Hans-Willi Mittrücker,Rolf A.K. Stahl,Ulf Panzer +15 more
TL;DR: For the first time, a beneficial effect of CXCR3 deficiency is demonstrated through attenuation of both the Th1 and the newly defined Th17 immune response, identifying the chemokine receptor CX CR3 as a promising therapeutic target in lupus nephritis.